Nicholls, D. P. and Davies, J. S. (1977). Thorax, 32, 472-477. Acid phosphatase activity in carcinoma of the bronchus. Two cases are presented in which an undifferentiated small-cell carcinoma of the bronchus was associated with a considerably raised serum tartrate-labile acid phosphatase concentration. In neither case was there any evidence of a carcinoma of the prostate which, with a few rare...

Phosphatase activities were investigated in Morganella morganii, which is one of the few enterobacterial species producing high-level phosphate-irrepressible acid phosphatase activity (HPAP phenotype), and the gene encoding the major phosphate-irrepressible acid phosphatase was cloned, sequenced, and its product characterized. Using p-nitrophenyl phosphate as substrate, Morganella produced a ma...

To evaluate the effects of polyphyllin D on proliferation and apoptosis human colon cancer SW480 cell lines to reveal whether this process is mediated by micro ribonucleic acid-21/phosphatase tensin homolog deleted chromosome 10 pathway. Human cells were transfected with acid-21-mimic or mimic-negative control treated at different concentrations (control, 0.25, 0.5, 1 2 μM) for 24 h 48 h. Compa...

Suspensions of Blepharisma intermedium were fed latex particles for 5 min and then were separated from the particles by filtration. Samples were fixed at intervals after separation and incubated to demonstrate acid phosphatase activity. They were subsequently embedded and sectioned for electron microscopy. During formation of the food vacuole, the vacuolar membrane is acid phosphatase-negative....

The phenotypic and quantitative relationship of red cell acid phosphatase with haemoglobin, haptoglobin, and G6PD phenotypes was investigated in three populations in the Sudan and one population in Nilgiris, India. No significant consistent association of red cell acid phosphatase phenotypes was observed with these polymorphisms. However, there was a lack of acid phosphatase AB in G6PD deficien...

1. The development, localization and heterogeneity of acid phosphatase and a Zn(2+)-activated acid phosphatase in cellular fractions of developing chick liver were studied. 2. Acid phosphatase is distributed abundantly in the particulate and soluble fractions. The soluble fraction is rich in Zn(2+)-activated acid phosphatase, which attains its peak activity at about 15 days of incubation. 3. Th...

The inhibitory effect of a marine-sponge toxin, okadaic acid, was examined on type 1, type 2A, type 2B and type 2C protein phosphatases as well as on a polycation-modulated (PCM) phosphatase. Of the protein phosphatases examined, the catalytic subunit of type 2A phosphatase from rabbit skeletal muscle was most potently inhibited. For the phosphorylated myosin light-chain (PMLC) phosphatase acti...

BACKGROUND: Clinical prostatic diseases occur in 80% of dogs over 5 and 95% over 9 years of age. . It seems that benign prostatic hyperplasia) BPH) affect Scottish terriers more severely than the other breeds. OBJECTIVES: This study aimed to evaluate the changes of biochemical and hematological parameters in BPH dogs. METHODS: Blood samples were collected from 10 male dogs older than five year...