Acne conglobata: very severe form of nodulocystic acne in which inflammatory lesions predominate and run together and often form exudates or bleed. Acne conglobata may cause extensive scarring. Acne fulminans: sudden, severe inflammatory reaction which causes deep ulcerations and erosions; may be associated with fever and arthralgia. Acne excoriée: mainly affects young women and is characterise...

The acronym of SAPHO syndrome (synovitis, acne, pustulosis, hyperostosis and osteitis) combines a cluster of cutaneous and musculoskeletal manifestations, such as hyperostosis of bones of the anterior chest wall associated with acne fulminans and hidradenitis suppurativa. There are no validated diagnostic criteria in children. Nonsteroidal anti-inflammatory drugs are not always sufficient, and ...

A 31-year-old male visited our hospital seeking dermato-logical care. He had been bodybuilding for a long time and had recently initiated a strict preparation program for a contest. To this end, he took intramuscular testosterone injections on three occasions , developing severe acneiform lesions. The course was gradual but progressive, leading to limitations in his daily activities, with arthr...

Background: In dermatology, the term sine is often used in regard to any sign, symptom or finding whose absence would very likely mean uncommon variant of the target disease or condition. Sine phenomenon can be seen in different dermatological diseases such as scleroderma, polymorphic light eruption, dermatomyositis, pellagra, zona, psoriasis, necrobiosis lipoidica, lupus erythematosus, seborrh...

INTRODUCTION Acne fulminans is a rare and severe form of acne characterized by the development of painful and inflammatory nodules on the face, chest, and back. Systemic signs are associated with the onset, including fever, chills, and musculoskeletal pain. Erythema nodosum, liver or spleen enlargement, myositis, or aseptic bone involvement have been reported more rarely. Its etiology remains u...

The authors report a case of SAPHO Syndrome, in pediatric age, with a dermatological focus. This entity should be considered in patients who have pain in the anterior chest wall or other musculoskeletal symptoms, accompanied by palmoplantar pustulosis and acne fulminans. The specific cutaneous manifestations, diagnosis and the treatment will be presented.

The acronym of SAPHO syndrome (synovitis, acne, pustulosis, hyperostosis and osteitis) combines a cluster of cutaneous and musculoskeletal manifestations, such as hyperostosis of bones of the anterior chest wall associated with acne fulminans and hidradenitis suppurativa. There are no validated diagnostic criteria in children. Nonsteroidal anti-inflammatory drugs are not always sufficient, and ...