نتایج جستجو برای: acridine 18 dione
تعداد نتایج: 359131 فیلتر نتایج به سال:
The title compound, C(18)H(20)O(4), was synthesized by the reaction of 4-methoxy-benzaldehyde, 2,2-dimethyl-1,3-dioxane-4,6-dione and 5,5-dimethyl-cyclo-hexane-1,3-dione with triethyl-benzyl-ammonium chloride in water as a green solvent. In the mol-ecule of the title compound, the six-membered pyran-one ring of the hexa-hydro-coumarin system has a screw-boat conformation while that of the dimet...
1. The metabolism of 4-[4-14C]androstene-3,17-dione, 4-[4-14C]pregnene-3,20-dione, 5a-[4-14C]androstane-3a,17f8-diol, [4-4C]cholesterol, 7a-hydroxy4-6fi-3H]cholesten3-one, 5fi-[7fi-3H]cholestane-3a,7U-diol and [3H]lithocholic acid was studied in the microsomal fraction of livers from control and orotic acid-treated male rats. 2. As a result of the treatment the orotic acid-fed rats had fatty li...
چکیده: در این تحقیق ابتدا چهار کمپلکس جدید از نیکل(ni) شامل،[ni (phen-dione) (en) (dafone)] (no3)2 [ni(phen-dione)(opd)(dioxime)](no3)2 [ni(phen-dione)(en)(dioxime)](no3)2,و [ni(phen- dione) (opd)(dafone)](no3)2 با لیگاندهای مختلف مشتق شده از فنانترولین (phen-dione =1,10- فنانترولین -6.5- دی اون، dafone = 4 ،5 -دی آزافلورن-9- اون، dioxime =1,10- فنانترولین – دی اکسیم، opd = اورتو فنیلن دی ...
The reaction of 6-amino-1,3-dimethylpyrimidine-2,4(1H,3H)-dione (1) as a binucleophile with primary aromatic or heterocyclic amines and formaldehyde or aromatic (heterocyclic) aldehydes in a molar ratio (1:1:2) gave the pyrimido[4,5-d]pyrimidin-2,4-dione ring systems 2-5. Treatment of 1 with diamines and formalin in molar ratio (2:1:4) gave the bis-pyrimido[4,5-d]pyrimidin-2,4-diones 6-8. Furth...
Pyrrolizine-1,3-dione 4 was made by oxidation of the alcohol 2 using pyridinium chlorochromate. The dione 4 shows ketone properties (e.g. formation of DNP derivative 11) and, in common with other pyrrolizinones, the lactam unit is readily ring-opened by methanol under basic conditions. The active methylene unit of 4 couples readily with diazonium salts to provide the hydrazone 15 whose structur...
در این پایان نامه برهمکنش پنج کمپلکس محلول در آب مس شامل[cu(phen)(phen-dione)cl]cl، [cu(bpy)(phen-dione)cl]cl ، [cu(4,7-biphphen)(phen-dione)cl]cl ,، [cu(4,7-dmp)(phen-dione)cl]cl و [cu(2,9-dmp)(phen-dione)cl]cl با ملکول dna در محلول و تثبیت شده بر روی الکترود اصلاح شده با کامپوزیت کیتوسان- کربن نانوتیوب مطالعه شده است. شیوه اتصال کمپلکسهای ذکر شده به dna در محلول، با استفاده از طیفهای جذبی مر...
The effect of temperature on the rate of proton transport and ATP hydrolysis by plasma membrane (PM) and tonoplast (TN) ATPases from barley (Hordeum vulgare L. cv CM 72) roots were compared. Rates of proton transport were estimated using the fluorescent amine dyes quinacrine and acridine orange. The ratio between rate of transport and ATP hydrolysis was found to depend on the dye, the temperatu...
The metabolism of 4-[4-Wlandrostene-3,17-dione, 4-[4r4C]pregnene-3,20-dione, 5&-[4-r4C]androstane-3cr,l7P-diol, 4,16-[70+~H]androstadien-3-one, [4-W]cholesterol, and 7~ hydroxy-4-[6P-3H]cholesten-3-one was studied in the microsomal fraction of livers from adult male and female rats which had been castrated neonatally or postpubertally. The effect of testosterone propionate treatment on postpube...
Parasitic diseases are of enormous public health significance in developing countries-a situation compounded by the toxicity of and resistance to many current chemotherapeutics. We investigated a focused library of 18 structurally diverse bis-acridine compounds for in vitro bioactivity against seven protozoan and one helminth parasite species and compared the bioactivities and the cytotoxicitie...
OBJECTIVE To investigate the anticancer properties of a chemosynthetic curcumin analog, (1E,6E)-4-((furan-2-yl)methylene)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione (C26H22O7, abbreviated MHMD) in A549 cells. MATERIALS AND METHODS Inverted microscope was used to observe the alteration on cytomorphology. MTT assay was used to detect cell viability. Acridine-orange staining was...
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