نتایج جستجو برای: acridinium ester
تعداد نتایج: 37135 فیلتر نتایج به سال:
Abstract Background Risankizumab is a human monoclonal antibody directed against the cytokine IL-23. This drug commonly used for treatment of patients with chronic inflammatory diseases such as psoriasis. about to get an indication in Crohn's disease and Ulcerative Colitis. Theradiag has just developed new rapid (results less than 40 minutes) innovative assays allowing quantification Risankizum...
A prototype, nonisotopic, chemiluminescent DNA probe test called the Gen-Probe PACE (Probe Assay-Chemiluminescence Enhanced) system for Neisseria gonorrhoeae (Gen-Probe, San Diego, Calif.) was compared with conventional Martin-Lewis culture medium in JEMBEC plates for the laboratory diagnosis of gonorrhea. This 2-h noncultural assay is based upon the use of an acridinium ester-labeled DNA probe...
Light-emitting chemical reactions (chemiluminescence, CL) and biological reactions (bioluminescence, BL) have a diverse range of analytical applications but relatively few have been adopted by routine clinical laboratories. Advantages of CL and BL assays include sensitivity (attomole and sub-attomole detection limits), speed (signal generated in a few seconds and in some cases stable for severa...
The title compound, C(13)H(10)N(+)·C(7)H(4)NO(4) (-)·H(2)O or (acrH)(+)(pydcH)(-)·H(2)O, is a monohydrate of acridinium cations and a mono-deprotonated pyridine-2,6-dicarb-oxy-lic acid. The structure contains a range of non-covalent inter-actions, such as O-H⋯O, O-H⋯N and N-H⋯O hydrogen bonds, as well as π-π stacking [range of centroid-centroid distances = 3.4783 (5)-3.8059 (5) Å]. The N-H⋯O hy...
We evaluated an immunochemiluminometric assay for total triiodothyronine (T3) in serum. Acridinium ester is used as chemiluminescent label, with magnetic particle separation. Intra-run precision was demonstrated by CVs of 8.6%, 8.1%, and 4.4% at T3 concentrations of 1.3, 2.2, and 4.3 nmol/L, respectively. Between-run CVs were 19.1%, 8.8%, and 6.9% at respective T3 concentrations of 0.9, 2.4, an...
We developed a competitive chemiluminoimmunoassay of osteocalcin that is similar to radioimmunoassay but uses acridinium-ester-labeled antigen instead of 125I-labeled osteocalcin; a second antibody immobilized on plastic beads is used to separate free and bound fractions. There was good correlation of the new chemiluminoimmunoassay (y) with a polyclonal antiserum (R102) radioimmunoassay (x) use...
Organochlorine pesticide endosulfan has been detected for the first time by using surface-enhanced Raman scattering (SERS) at trace concentrations. The bis-acridinium dication lucigenine was successfully used as a molecular assembler in the functionalization of metal nanoparticles to facilitate the approach of the pesticide to the metal surface. From the SERS spectra valuable information about ...
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