This study investigated changes in the coagulation profile of 10 healthy female dogs subjected to ovariohysterectomy. Blood samples were collected three times--before, directly after and 24 h after surgery. Plasma samples were analyzed to determine thrombin time (TT), prothrombin time (PT), activated partial thromboplastin time (APTT), fibrinogen content, D-dimer content and antithrombin (AT) I...

Simultaneous or sequential haemorrhage and thrombosis in the presence of a prolonged activated partial thromboplastin time (aPTT) is a rare occurrence: we describe the case a 37 year old lady who developed post-delivery deep vein thrombosis treated with low molecular heparin and warfarin followed a week later by extensive bruising over legs and forearms, a significant drop in haemoglobin and a ...

Impact of gestational diabetes mellitus (GDM) on the coagulation system still remains unclear and there is limited data available regarding haemostatic changes in GDM Bangladesh. This study was aimed at determining plasmaprothrombin time (PT), activated partial thromboplastin (APTT) women with GDM. cross sectional encompassed 44 (age: 28.5±3.8 years, BMI: 27.2±4.0kg/m2; mean±SD) equal number pr...

Objective: Heparins can interfere with lupus anticoagulant (LA) testing, especially when the detection assays do not contain a heparin neutralizer. In this study we evaluated whether hexadimethrine bromide commonly known as polybrene was able to neutralize effects of unfractionated (UFH) on activated partial thromboplastin time (aPTT)-based LA determination. Material and Methods: The influence ...

Hepatitis B Viral (HBV) infection is a condition of inflammation the liver. The Liver plays vital role in body which includes filtration blood, production coagulation proteins and also as storage organ. In this study, alteration some parameters include, Prothrombin time (PT), activated partial thromboplastin (APTT), Platelets counts (PLATS) were determined sixty (60) known seropositive individu...

Objective: This study aims to investigate the relationship between prothrombin time (PT), activated partial thromboplastin (aPTT), INR (International Normalized Ratio), and D-dimer levels, platelet (PLT) levels at hospital admission, positivity or negativity of Polymerase Chain Reaction (PCR) test results in patients with suspected coronavirus disease-19 (COVID-19) followed COVID-19 services.&#...

The prothrombin time (PT) and activated partial thromboplastin time (APTT) are among the most commonly ordered coagulation tests. In 2005, more than 140,000 PT and more than 95,000 APTT tests were performed at Mayo Clinic. The most common indications for ordering these tests include anticoagulant monitoring, initial evaluation of hemorrhage, and, although not generally indicated, routine preope...

We looked into the statistical association of prothrombin time (PT) and activated partial thromboplastin time (APTT) with disseminated intravascular coagulation (DIC) score calculated using the International society for thrombosis and haemostasis (ISTH) scoring system. The PT, APTT, PT + APTT, and PT/APTT ratios were evaluated against the DIC score by linear regression analysis in fifty inpatie...