We used an RIA and inhibition of enzyme activity to monitor the changes in mass and catalytic concentrations of the aspartate aminotransferase (EC 2.6.1.1;AST) isoenzymes in serum after myocardial infarction. Cytosolic (c-AST) and mitochondrial (m-AST) forms of AST were present in sera from all 38 of our patients. Although the immunological and catalytic concentrations of both isoenzymes correl...

AIMS To study the synergistic effect of occupational chemical exposure and hepatitis virus infection on serum aminotransferase activity. METHODS A total of 568 male workers who were employed in five polyvinyl chloride (PVC) or four vinyl chloride monomer (VCM) manufacturing factories were studied. Information relating to current job title, alcohol consumption, and cigarette smoking was obtain...

background: paraquat is a non-selective contact herbicide, widely used to control weeds in agriculture farms and aquatic plants in surface waters. paraquat can have adverse effects on the health of aquatic organisms. the aim of this study was to detect the alterations in the blood biochemical parameters of common carp exposed to sub-lethal concentrations of commercial formulations of paraquat. ...

The activity of aspartate aminotransferase, alanine aminotransferase and lactate dehydrogenase, total protein, albumin and cholesterol levels were determined in the blood serum of Japanese quails infected with coccidia and treated with Baycox (active ingredient: toltrazuril). Lower levels of AST and ALT activity were noted in treated birds regardless of the applied Baycox dose. The biochemical ...

High doses of acetaminophen (APAP) lead to acute liver damage. In this study, we evaluated the effects of citral in a murine model of hepatotoxicity induced by APAP. The liver function markers alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), and gamma-glutamyl transferase (γGT) were determined to evaluate the hepatoprotective effects of citral. The l...

objective(s): methylsulfonylmethane (msm) is a sulfur-containing compound found in a wide range of human foods including fruits, vegetables, grains and beverages. in this study the effect of msm pretreatment on acetaminophen induced liver damage was investigated. materials and methods: male sprague dawley rats were pretreated with 100 mg/kg msm for one week. on day seven rats were received acet...

previous studies indicated that endurance exercise decreases levels of liver enzymes. the aim of this study was to determine the effect of endurance exercise on liver enzymes in eight weeks in iranian women who are stopping the drug with methadone. sixty iranian women prisoners including 30 cases as experimental group and 30 volunteers served as control. the mean age, height, weight, percent of...