نتایج جستجو برای: addiction biology studies
تعداد نتایج: 1578329 فیلتر نتایج به سال:
This issue of Alcohol Research & Health examines addiction to multiple substances--that is, combined dependence on alcohol and other drugs (AODs), including marijuana, cocaine, and opioids. It seems fitting, then, to begin the issue with a look at what constitutes "addiction." The Oxford English Dictionary (pp. 24-25) traces the term addiction to Roman law, under which addiction was a "formal g...
Professor Otto Lesch, with more than 30 years experience in the field, and his colleagues deal in this book with two substances -alcohol and tobaccoand the many aspects of their use, abuse and addiction: medical, psychiatric, psychological, biological, pharmacological, and sociological. Alcohol and nicotine abuse and addiction usually occur together. Therapeutic pharmacological, psychotherapeut...
for a long time, scientists have tried to describe disorders just by genetic or environmental factors. however, the role of epigenetics in human diseases has been considered from a half of century ago. in the last decade, this subject has attracted many interests, especially in complicated disorders such as behavior plasticity, memory, cancer, autoimmune disease, and addiction as well as neurod...
Lewis's review of my book (2011, this issue) repeats widely shared understandings of the nature of addiction and the role that dopamine plays in the persistence of self-destructive drug use. These accounts depict addiction as a chronic relapsing disease and claim that drug-induced changes in dopamine function explain the transition from drug experimentation to compulsive drug use. In my book, I...
Opioid receptors are important drug targets for pain management, addiction, and mood disorders. Although substantial research on these important subtypes of G protein-coupled receptors has been conducted over the past two decades to discover ligands with higher specificity and diminished side effects, currently used opioid therapeutics remain suboptimal. Luckily, recent advances in structural b...
Institute of Computational Biology, Helmholtz Zentrum München, 85764 Neuherberg, Germany Chair of Mathematical Modeling of Biological Systems, Center for Mathematics, Technische Universität München, 85748 Garching, Germany Alacris Theranostics GmbH, 12489 Berlin, Germany Max Planck Institute for Molecular Genetics, 14195 Berlin, Germany Dahlem Centre for Genome Research and Medical Systems Biol...
Classical genetic research approaches to determining the genetic contribution to a multifactorial condition have been used to quantify the proportion of addiction and substance abuse that is a result of heritable genetic factors versus environmental factors. Family studies, twin studies, and adoption studies have all been applied for individuals and families with a history of addiction and subs...
The advent and development of new technologies around the world have turned the use of smartphones into an essential part of human life. But in spite of its positive aspects, the overuse and addiction to this new tool have become an important subject. Smartphone addiction can affect many aspects of one’s life. In the present study, we collected 512 scientific studies by searching the keywords “...
Cigarette smoking is still a major cause of many preventable diseases [1]. The pharmacologic effect of nicotine plays a crucial role in tobacco addiction [1,2]. When issues around tobacco use are considered, “nicotine addiction” can be regarded as a roadblock that needs to be overcome. The importance of nicotine in maintaining smoking and in cessation difficulty has been well acknowledged [3]. ...
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