نتایج جستجو برای: adenosine deaminase ada
تعداد نتایج: 118967 فیلتر نتایج به سال:
conclusions serum ada activity with high specificity percentage may be a useful alternative test in restricted resource areas to rule out diagnosis of ptb. however, serum ada activity is not a useful tool for tb diagnosis. mean serum ada level in the ptb group was clearly higher than the mean serum ada in the other three groups. mean serum ada was 26 iu/l in ptb patients, 19.48 iu/l in patients...
Adenosine deaminase (ADA) was detected immunohistochemically in neuronal cell bodies of dorsal root ganglia (DRG) of the rat. ADA-immunoreactivity was confined exclusively to small type B ganglion neurons in cervical, thoracic and lumbar sensory ganglia; large type A neurons in sensory ganglia were devoid of immunostaining for ADA. It was consistently found that only a small proportion of type ...
Aim: This study aims to investigate the possible effects of aqueous Echinacea (E. Purpurea, whole plant) extract on Adenosine deaminase (ADA) activity in cancerous and non-cancerous human gastric and colon tissues. Materials and Methods: Thirty three cancerous and 33 non-cancerous human gastric tissues, and 25 cancerous and non-cancerous human colon tissues removed by surgical operations were s...
background and objective: brucellosis is a main transmittable zoonotic disease, which is endemic, and a common health burden in iran. adenosine deaminase (ada) is an essential enzyme which is involved in purine metabolism and its role in immune system is very important. the aim of this study was to determine serum changes of ada and c-reactive protein (crp) levels in patients with brucellosis. ...
Adenosine Deaminase (ADA) deficiency is an autosomal recessive variant of severe combined immunodeficiency (SCID) caused by systemic accumulation of ADA substrates. Neurological and behavioral abnormalities observed in ADA-SCID patients surviving after stem cell transplantation or gene therapy represent an unresolved enigma in the field. We found significant neurological and cognitive alteratio...
The effects of allopurinol, acyclovir and theophylline on the activity of adenosine deaminase (ADA) were studied in 50 mM sodium phosphate buffer pH 7.5 at 27°C, using a UV– Vis spectrophotometer. Adenosine deaminase is inhibited by these ligands, via different types of inhibition. Allopurinol, as a transition state analog of xanthine oxidase, and acyclovir competitively inhibit the catalytic a...
The effects of allopurinol, acyclovir and theophylline on the activity of adenosine deaminase (ADA) were studied in 50 mM sodium phosphate buffer pH 7.5 at 27°C, using a UV– Vis spectrophotometer. Adenosine deaminase is inhibited by these ligands, via different types of inhibition. Allopurinol, as a transition state analog of xanthine oxidase, and acyclovir competitively inhibit the catalytic a...
Adenosine exerts neuromodulatory functions with mostly inhibitory effects, being considered an endogenous anticonvulsant. The hydrolysis of ATP by ectonucleotidases is an important source of adenosine, and adenosine deaminase (ADA) contributes to the regulation of this nucleoside concentration through its deamination. In this study, we tested the effect of pentylenetetrazole (PTZ)-induced seizu...
The binding characteristics of [3H]nitrobenzylthioinosine ([3H]NBI) to rat brain membrane preparations was examined, and the autoradiographic distribution of this ligand in brain sections was compared with the immunohistochemical localization of adenosine deaminase (ADA). It was found that [3H]NBI labels sites for which adenosine has far higher affinity than do other nucleosides, that these sit...
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