Several environmental factors regulate the expression of virulence genes under certain conditions and the expression of bacterial virulence determinants. Cytolethal distending toxin (CDT) is an important virulence determinant secreted by Campylobacter jejuni (C. jejuni), a leading cause of gastrointestinal bacterial pathogen worldwide. Therefore, the aim of the study was to investigate the effe...

The Gram-negative Pseudomonas aeruginosa bacterial pathogen is reputed for its resistance to multiple antibiotics, and this property is strongly associated with the development of biofilms. Bacterial biofilms form by aggregation of microorganisms on a solid surface and secretion of an extracellular polysaccharide substances that acts as a physical protection barrier for the encased bacteria. In...

Group A streptococci produce a wide variety of extracellular (cell-associated and released) virulence factors. The function of these factors varies and includes roles in adhesion, spreading, tissue destruction, immune system evasion, and cell toxicity. How these factors are regulated with regard to one another is important for this organism s ability to bring about the variety of diseases this ...

background and objectives: pseudomonas aeruginosa possesses a variety of virulence factors that may contribute to its pathogenicity. the aim of this study was to evaluate opri , oprl and toxa genes for pcr identification of clinical p. aeruginosa . in order to find out any relation between special virulence factors and special manifestation of p. aeruginosa infections, we detected virulence fac...

conclusions: high percentage of hemolysins, biofilm and beta lactamase production by isolated staphylococci, suggests an important role of these virulence factors in the pathogenesis of isolated staphylococci from dermatitis lesions. the s. aureus isolates from wound infections, show a high sensitivity pattern to all examined antibiotics. only ciprofloxacin was found to be active against all is...

background putative virulence factors are responsible for the pathogenicity of utis caused by pseudomonas aeruginosa (p. aeruginosa). resistance of p. aeruginosa to commonly used antibiotics is caused by the extreme overprescription of those antibiotics. objectives the goal of the present study was to investigate the prevalence of virulence factors and the antibiotic resistance patterns of p. a...

extra-intestinal pathogenic escherichia coli (expec) strains are divided into uropathogenic e. coli (upec), strains causing neonatal meningitis and septicaemic e. coli. the most common pathotype of expec is found among patients with urinary tract infection (uti), defined as upec. these bacteria are responsible for >90% of cases of uti and are often found amongst the faecal flora of the same hos...

helicobacter pylori infection is a common gastrointestinal infection that can cause pathological effects, increase oxidative stress and induce an inflammatory response in gastric mucosa. inflammatory aspects may prompt the production of radical oxygen substance (ros) which may damage cells and release 8-hydroxydyoxyguanosine (8-ohdg) to serum. in this study, we evaluate the prevalence of h. pyl...

Candida albicans is a fungus that often colonizes the human body as commensal without causing any symptoms. Several C. virulence factors have been described in literature, of which best known are adhesion to host mucosa cells and secretion hydrolytic enzymes. The transition from colonization infection depends not only on fungus, but also response invasion. This literature review focuses differe...

Blastocystis is an extracellular, enteric pathogen that induces intestinal disorders in a range of hosts including humans. Recent studies have identified potential parasite virulence factors in and host responses to this parasite; however, little is known about Blastocystis-host attachment, which is crucial for colonization and virulence of luminal stages. By utilizing 7 different strains of th...