during a period of is years from 1975 to 1989, eleven children with adrenocortical tumors were managed with relatively favorable results in our center. despite its rarity in the pediatric age group, our series is one of the largest reported in the literature in the given period of time. all of our 11 patients presented with hyperfunction of the adrenal cortex. virilization alone was the most fr...

Clinically silent adrenal masses discovered by imaging studies performed for unrelated reasons, i.e. adrenal incidentalomas, have become a rather common finding in clinical practice. However, only limited studies of incidence, prevalence, and natural history of adrenal incidentalomas are available. A comprehensive review of the literature shows the prevalence of adrenal incidentalomas to be 2.3...

The benefits of laparoscopic adrenalectomy for single adrenal lesion have been well documented in literature; less experience though has been reported with simultaneous bilateral laparoscopic adrenalectomy. This operation is indicated in case of primary hypercortisolism caused by bilateral adrenocortical hyperfunction, Cushing's disease after failure of pituitary surgery, ectopic adrenocorticot...

Aberrant gastric inhibitory polypeptide (GIP) receptor expression in bilaterally hyperplastic adrenals or unilateral adrenal adenomas is a rare form of adrenal hyperfunction. So far, only few cases have been described. In all these cases, cortisol was the predominant steroid released in a food-dependent manner, leading to the development of non-ACTH-dependent Cushing's syndrome. In the present ...

The adrenal cortex acts by the elaboration of a series of "hormones which include among their functions the regulation of the electrolyte balance; carbohydrate, fat and protein metabolism; the development of the secondary sexual characteristics; and possibly the development of the gonads themselves. Although the action of many of these hormones is regulated by the pituitary, the latter gland ha...

Adrenocortical carcinoma is an uncommon and aggressivemalignancy. Despite a high frequency of metastasis, cutaneousmetastasis of adrenocortical carcinoma is rare with only isolatedcase reports. Its diagnosis can be challenging based solely onhistopathological findings. Yet, the clinical history in combinationwith an immunohistochemical panel consisting of inhibin,vimentin, chromogranin, synapto...

BACKGROUND This study was designed to evaluate the clinical, endocrinological and histological characteristics of adrenal incidentalomas. METHODS Eighty patients (41, males; 38, females; age range 17-80 years) who were diagnosed with adrenal incidentaloma at Korea University Hospital from 1992 to 2003 were studied retrospectively. RESULTS Endocrinological investigation revealed 16 pheochrom...

This is the second paper on invariant hyperfunction solutions of invariant linear differential equations on the vector space of n × n real symmetric matrices. In the preceding paper [22], we proved that every invariant hyperfunction solution is expressed as a linear combination of Laurent expansion coefficients of the complex power of the determinant function with respect to the parameter. Fund...

nonfunctional adrenocortical carcinoma is an extremely rare malignant tumor in children. unlike the functional tumor which is detected early due to its hormonal presentation, nonfunctional tumor is detected at a later stage. here we report a case of a 10 year old girl who presented with abdominal mass and symptoms of short duration. no hypertension and cushingoid features were seen. serum alpha...