نتایج جستجو برای: alcoholic

تعداد نتایج: 34189  

2016
Aleksandra Filippova

The objective of the research was to study the features of the indicators of the humoral component of the immune system depending on the body mass index in patients with non-alcoholic hepatic steatosis, non-alcoholic steatohepatitis, concomitant obesity and biliary tract pathology. Material and methods. 200 patients with non-alcoholic fatty liver disease, concomitant obesity and biliary tract p...

Journal: :Indian journal of physiology and pharmacology 2003
Suresh Chari Madhur Gupta

Chronic alcohol consumption is associated with increased incidence of variety of illnesses including cirrhosis. Studies have shown that ethanol consumption may result in increased oxidative stress with increased formation of lipid peroxides and free radicals. However, very few reports are available on their involvement in the toxicity of alcoholic cirrhosis. The present study was undertaken in ...

Journal: :The American journal of clinical nutrition 1988
E Mezey C J Kolman A M Diehl M C Mitchell H F Herlong

Alcohol and dietary intake were determined in alcoholic patients with chronic pancreatitis and alcoholic liver disease. Patients with chronic pancreatitis, alcoholic hepatitis, and cirrhosis ingested approximately 50% of their calories as alcohol, and all had low mean intakes of protein, carbohydrate, and fat as compared with control subjects. Patients with severe alcoholic hepatitis had the lo...

2001
Nam-Ik Han Kyu-Won Chung Byung-Min Ahn Sang-Wook Choi Young-Sok Lee Chang-Don Lee Hee-Sik Sun

BACKGROUND Hepatic stellate cell (HSC) has been suggested to play a role in fibrogenesis in alcoholic liver disease. We evaluate the correlation with fibrogenesis and ultrastructure of hepatic stellate cells in alcoholic fatty liver. METHODS We studied 6 patients with alcoholic fatty liver and 5 non-alcoholic fatty liver. The numbers of fat droplets in hepatic stellate cell was determined by ...

Journal: :Journal of clinical pathology 1983
J Burns A J D'Ardenne J A Morton J O McGee

A Mallory body (alcoholic hyaline) antigen (JMB2) which is also present in intermediate filaments of epithelial origin was demonstrated immunohistochemically in renal glomeruli of three out of eleven patients with alcoholic liver damage. In two of these patients, both of whom had alcoholic cirrhosis with Mallory bodies, it was associated with mesangial deposits of IgA and C3. JMB2 was not found...

2006
B. Gopalakrishnan Adesh A. Bawane Kusum S. Akki V.I. Hukkeri

To evaluate the free radical scavenging activity of flavonoids containing extracts of Stevia leaf. Alcoholic. Successive butanolic and alcoholic extracts of leaves were examined for free radical scavenging activity using BHT (tert-butylhydroxytolune) as a positive control by in vitro models. Successive alcoholic extract showed remarkable free radical scavenging activity. The IC(50) was found to...

2014
Metin Küçükazman Naim Ata Kürşat Dal Abdullah Özgür Yeniova Ayşe Kefeli Sebahat Basyigit Bora Aktas Kadir Okhan Akin Kadir Ağladioğlu Öznur Sari Üre Firdes Topal Yaşar Nazligül Esin Beyan Derun Taner Ertugrul

OBJECTIVE Vitamin D deficiency has been related to diabetes, hypertension, hyperlipidemia and peripheral vascular disease. In this study, we aimed to investigate the role of vitamin D status in non-alcoholic fatty liver disease. METHODS We included 211 consecutive subjects to examine the presence of non-alcoholic fatty liver disease. Of these subjects, 57 did not have non-alcoholic fatty live...

2012
Jonas Rosendahl Anke Tönjes Dorit Schleinitz Peter Kovacs Johannes Wiegand Claudia Ruffert Moritz Jesinghaus Robert Schober Max Herms Robert Grützmann Hans-Ulrich Schulz Felix Stickel Jens Werner Peter Bugert Matthias Blüher Michael Stumvoll Stephan Böhm Thomas Berg Henning Wittenburg Joachim Mössner Rene te Morsche Monique Derikx Volker Keim Heiko Witt Joost P. H. Drenth

BACKGROUND Chronic pancreatitis (CP) is an inflammatory disease that in some patients leads to exocrine and endocrine dysfunction. In industrialized countries the most common aetiology is chronic alcohol abuse. Descriptions of associated genetic alterations in alcoholic CP are rare. However, a common PNPLA3 variant (p.I148M) is associated with the development of alcoholic liver cirrhosis (ALC)....

2018
Benjamin L. Woolbright Hartmut Jaeschke

Alcoholic hepatitis is the most severe and acute form of alcoholic liver disease. The mortality rate associated with alcoholic hepatitis is high, largely due to the lack of suitable pharmacological interventions. While there has been substantial research in the area, generating pharmacological interventions has been plagued by the lack of a robust mouse model both for testing and for understand...

Journal: :Gut 1979
S W Mann G C Fuller J V Rodil E I Vidins

Hepatic prolyl hydroxylase activity and collagen synthesis were measured in patients with alcoholic liver disease to determine the feasibility of using the enzyme prolyl hydroxylase as a marker of hepatic fibrogenesis. Alcoholic patients with liver histopathology consistent with normal, steatosis, alcoholic hepatitis, early cirrhosis, or advanced cirrhosis were analysed for liver prolyl hydroxy...

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