Background: Diabetes mellitus (DM) is a metabolic disease of the endocrine system, characterized by chronic hyperglycemia, resulting either from insulin resistance or defective production due to dysfunction pancreatic ?-cells. Approximately 80% diabetic patients live in developing and underdeveloped countries. Pakistan ranked on 7th position regarding prevalence DM. In developed nations, DM 4th...

Aloe vera (Aloe arborescens, aloe barbadensis) is a medicinal plant belonging to the Liliaceae family. Aloe vera gel prepared from the inner part of Aloe leaves is increasingly consumed as a beverage dietary supplement. Some data suggest its tumor growth modulatory properties. The aim of the present study was to evaluate in Balb/c mice the in vivo influence of orally administered Aloe vera drin...

BACKGROUND Ten (10) young women diagnosed with human immunodeficiency virus (HIV) infection in the Wesley Guild Hospital Ilesa, a unit of Obafemi Awolowo University Teaching Hospital, Ile Ife, Osun State, Nigeria who did not meet the national criteria for the use of antiretroviral drugs were managed with 30-40 mL of aloe vera (Aloe barbadensis miller) gruel daily. METHODS Their CD4 counts, ge...

morbidity and mortality in the world. About 2.5—3% of the world’s population suffers from this disease, a proportion which, in some countries, can reach 7% or more. Hyperglycemia leads to metabolic disorders and various complications. There is increasing evidence indicating that enhanced production of free radicals may be an important contributing factor in the complications seen in diabetes. S...

This is a preliminary study that explores the efficacy of Aloe vera gel formulation as a possible therapeutic agent in the prevention and management of polycystic ovary syndrome (PCOS). PCOS is recognized as the most common endocrinopathy of women. Increased androgen synthesis, disrupted folliculogenesis, and insulin resistance lie at the patho-physiological core of PCOS. Current therapy for su...

OBJECTIVES Aloe barbadensis miller or Aloe vera has been used for therapeutic purposes since ancient times with antifungal activity known to be amongst its medicinal properties. We conducted a pilot study to determine the antifungal properties of Malaysian Aloe vera leaf extract on otomycosis species including Aspergillus niger and Candida albicans. METHODS This laboratory-controlled prospect...

This study reports on the acute toxic effects of Aloe barbadensis Miller (Aloe vera) juice as well as high doses of the antioxidants vitamin C, vitamin E and TroloxTM (a water soluble vitamin E analogue) to the salt water crustacean Artemia franciscana. Aloe vera juice exposure resulted in acute toxicity, being capable of inducing mortality at dilutions as low as 4 % juice and having an LC50 at...