نتایج جستجو برای: alzheimer disease
تعداد نتایج: 1493098 فیلتر نتایج به سال:
background: metal ions effect on homeostasis of alzheimer’s disease (ad) patients. the aim of this study was to assess the metal ions (iron, zinc and copper) and cbc in patients with ad in comparison with normal range. methods: the samples of study were 17 patients with ad in tehran’s aging centers in 2015, selected as an access sample. blood samples were analyzed in a pathobiology laboratory. ...
background: sporadic alzheimer’s disease (sad) is caused by genetic risk factors, aging and oxidative stresses. the herbal extract of rosa canina (r. canina), tanacetum vulgare (t. vulgare) and urtica dioica (u. dioica) has a beneficial role in aging, as an anti-inflammatory and anti-oxidative agent. in this study, the neuroprotective effects of this herbal extract in the rat model of sad was i...
P 59: Non-Steroidal Anti-Inflammatory Drugs as a Prevention of Alzheimer Disease: Risks and Benefits
Alzheimer's disease (AD) is a chronic neurodegenerative disease that accounts for 60 to 80 percent of all dementia cases. The exact cause of Alzheimer`s disease is still unknown, but recent studies suggest neuro-inflammation as an important part of the pathogenesis of the disease. This brings in mind using non-steroidal anti-inflammatory drugs (NSAID) as treatment or prevention of the disease. ...
introduction:brain imaging with f-18 fluorodeoxyglucose (18f-fdg) positron emission tomography or tc-99m hexamethylpropyleneamine oxime (99mtc-hmpao) spect is widely used for the evaluation of alzheimer's dementia (ad); we aim to assess superiority of one method over the other. methods: twenty four patients with clinical diagnosis of alzheimer disease underwent 18f-fdg pet and 99mtc-...
During November 2012-July 2013, a marked increase of adenovirus type 7 (Ad7) infections associated with severe disease was documented among pediatric patients in Singapore. Phylogenetic analysis revealed close genetic links with severe Ad7 outbreaks in China, Taiwan, and other parts of Asia.
We don’t understand Alzheimer, its origin and disease mechanisms. The absence of disease-modifying treatments for Alzheimer today is due to the amyloid hypothesis, a misguided hypothesis of Alzheimer’s etiology, which has dominated research, drug development, clinical trials 30 years. However, the hypothesis is not dead yet, as exemplified by the recent resurrection of clinical with aducanumab....
background and objective: alzheimer’s disease (ad) is a multifactorial disease with debilitating consequences and few therapeutic strategies exist for it. with regard to antioxidant capacity and anti-β-amyloid polymerization potential of ellagic acid, this study was conducted to evaluate the effect of this substance on enhanced acetylcholinesterase reactivity in an experimental model of alzheim...
introduction: to study the effect of gallic acid (ga) on hippocampal long-term potentiation (ltp) and histological changes in animal model of alzheimer disease (ad) induced by betaamyloid (aβ). methods: sixty-four adult male wistar rats (300±20 g) were divided into 8 groups: 1) control (cont); 2) ad; 3) sham; 4-7) ad+ga (50, 100, and 200 mg/kg for 10 days, orally) or vehicle, 8) cont+ga100, aβ ...
alzheimer's disease (ad), a common and debilitating neurodegenerative disorder, affect more than 65 million individuals throughout the world. this disability plays a crucial role in daily activities such as driving. several studies have investigated the relationship between cognitive functions and driving safety. the current study revises the literature on the relation between road safety ...
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