Alzheimer's disease (AD) is a chronic neurodegenerative disease that accounts for 60 to 80 percent of all dementia cases. The exact cause of Alzheimer`s disease is still unknown, but recent studies suggest neuro-inflammation as an important part of the pathogenesis of the disease. This brings in mind using non-steroidal anti-inflammatory drugs (NSAID) as treatment or prevention of the disease. ...

introduction:brain imaging with f-18 fluorodeoxyglucose (18f-fdg) positron ‎emission tomography or tc-99m hexamethylpropyleneamine oxime (‎99mtc-hmpao) spect is widely used for the evaluation of alzheimer's ‎dementia (ad); we aim to assess superiority of one method over the ‎other. methods: twenty four patients with clinical diagnosis of alzheimer disease ‎underwent 18f-fdg pet and ‎99mtc-...

the most popular animal models of alzheimer’s disease (ad) are transgenic mice expressing human genes with known mutations which do not represent the most abundant sporadic form of the disease. an increasing number of genetic, vascular and psychosocial data strongly support that the octodon degus, a moderate-sized and diurnal precocial rodent, provides a naturalistic model for the study of the ...

neurodegenerative disease are characterized by the progressive loss of neurons from specific origins of the cns .alzheimer disease (ad) is a neurodegenerative disorder which affect brain regains that control memory and ability to learn. it is estimated that 27 million people are affected word wide and this number is expected to triple by 2050 due to increase of the population life expectancy. a...

The prevalence of major depression is increased in Alzheimer disease (AD), but currently the basis of this association remains unclear. The present study examined rates of depression in 4 groups of participants with postmortem examination from the Baltimore Longitudinal Study of Aging: (1) cognitively normal controls with no Alzheimer pathology, (2) cognitively normal individuals with Alzheimer...

Neurodegenerative disease are characterized by the progressive loss of neurons from specific origins of the CNS .Alzheimer disease (AD) is a neurodegenerative disorder which affect brain regains that control memory and ability to learn. It is estimated that 27 million people are affected word wide and this number is expected to triple by 2050 due to increase of the population life expectancy. A...

A growing body of evidence suggests that vascular disease underlies Alzheimer dementia. Atherosclerotic lesions in the circle of Willis and large leptomeningeal vessels were quantified and found to correlate with Alzheimer disease (AD) clinical diagnosis and neuropathology. We hypothesize that AD pathology is the complex end result of slowly evolving vascular disease and parenchymal lesions. Co...