background :   keratitis caused by pseudomonas  aeruginosa   is often resulted in  severe  corneal  ulcers  and  perforation,  which  leads  to  losses  of  vision. human amniotic membrane (ham) forms the inner wall of the membranous sac which surrounds and protects the embryo during gestation. the purpose of this  study  was  to  evaluate  the  effectiveness  of  the  amniotic  membrane's heal...

background: radiotherapy is one of the most important factors which results in negative effects on wound healing and increases anastomosis leakage. diverting loop ileostomy has been usually performed after colorectal anastomosis in cases of colorectal cancer with a history of neoadjuvant radiotherapy to decrease the chance of leakage. considering the side effects of diverting loop ileostomy, th...

purpose: to evaluate the effect of aamniotic mmembrane ttransplantation (amt) in the management of acute severe ocular chemical burns. methods: this randomized clinical trial was performed in eligible patients with grade iii & iv acute chemical burn who randomly received conventional medical therapy (15 eyes) versus combined medical & amniotic membrane transplantation (15 eyes). main outcome me...

background mesenchymal stem cells (mscs) are ideal candidates for treatment of diseases. amniotic membranes are an inexpensive source of mscs (am-msc) without any donor site morbidity in cell therapy. adipose tissue derived stem cells (ascs) are also suitable cells for cell therapy. there is discrepancy in cd271 expression among mscs from different sources. in this study, the characteristics of...

background and aim: the aim of the present study was to compare coronally advanced flap (caf) with amniotic membrane to caf with connective tissue graft (ctg) in the treatment of miller’s class iⅈ gingival recessions. materials and methods: 11 systemically healthy patients, with 30 miller’s class і and іі gingival recessions ≥3 mm, were selected and randomly divided into two equal groups. gi...

purpose: to evaluate the properties of cultured limbal stem cells for corneal surface reconstruction. methods: specimens of limbal explants were prepared from the eye bank of i.r. iran. the explants were cultured and expanded on acellular amniotic membrane for 21 days. the cultured cells were evaluated for expression of connexin 43 and keratinine k3 by immunocytochemistry and expression of k12 ...

BACKGROUND Mesenchymal stem cells (MSCs) are ideal candidates for treatment of diseases. Amniotic membranes are an inexpensive source of MSCs (AM-MSC) without any donor site morbidity in cell therapy. Adipose tissue derived stem cells (ASCs) are also suitable cells for cell therapy. There is discrepancy in CD271 expression among MSCs from different sources. In this study, the characteristics...

the past decade has witnessed the revival of amniotic membrane transplantation (amt) in ophthalmology. the importance of amt is due to its ability to reduce scarring and inflammation and to enhance wound healing and epithelialization, and also its anti-microbial properties. amniotic membrane has recently been used as a substrate for culturing limbal stem cells for transplantation. it has been u...