and normal tissues. The nature and extent of such effects, however, depend on selected biological parameter (e.g., oxygen supply, cell cycle) and can be modified by chemical agents such as radiosensitizers, radioprotectors and chemotherapeutic agents. A precise control of the mode of action of the radiation is important in order to achieve the maximum effect on tumor tissue, while minimizing th...

Anticancer activity of various doses of alcoholic extract of rohituka, Aphanamixis polystachya (APE) was studied in mice transplanted with Ehrlich ascites carcinoma (EAC). Administration of 0, 0.125, 0.25, 0.5, 0.75, 1, 1.25 or 1.5 g/Kg body weight APE once daily for consecutive 9 days resulted in a dose dependent regression in the tumor mass and increase in tumor-free survivors. The greatest a...

Though many of the presently used anticancer drugs are originated or derived from plants, an attempt to the isolation and clinical usage of single compound has caused severe adverse side effects like, myelosuppression, alopecia, nausea, gastrointestinal, reproductive and nephrotoxicity. In addition, most of the modern chemotherapeutic agents have been reported to induce secondary malignancies d...