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The recent complete ban on the use of the antibiotic growth promoting substances by the EU and partly in several other countries worldwide urged nutritionists and animal scientists to seek for alternatives. The use of organic acids in poultry and pig nutrition appears to be an interesting solution that can enhance the eff ect of other feed additives, as well. In combination with other substance...
Large-scale force generation is essential for biological functions such as cell motility, embryonic development, and muscle contraction. In these processes, forces generated at the molecular level by motor proteins are transmitted by disordered fiber networks, resulting in large-scale active stresses. Although these fiber networks are well characterized macroscopically, this stress generation b...
Dendritic spines mediate most excitatory synapses in the brain. Past theoretical work and recent experimental evidence have suggested that spines could contain sodium channels. We tested this by measuring the effect of the sodium channel blocker tetrodotoxin (TTX) on depolarizations generated by two-photon uncaging of glutamate on spines from mouse neocortical pyramidal neurons. In practically ...
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