Miguel G. Echevarria, Ignazio Scimemi, and Alexey Vladimirov Nikhef Theory Group, Science Park 105, 1098XG Amsterdam, The Netherlands Department of Physics and Astronomy, VU University Amsterdam, De Boelelaan 1081, NL-1081 HV Amsterdam, The Netherlands Departamento de Física Teórica II, Facultad de Ciencias Físicas, Universidad Complutense de Madrid, 28040 Madrid, Spain Institut für Theoretisch...

PURPOSE Hereditary nonpolyposis colorectal cancer (HNPCC) is the commonest form of inherited colorectal cancer. Whereas it has been known that mismatch repair gene mutations are the underlying cause of HNPCC, an undetermined number of patients do not have these alterations. The main objectives of this study were to assess the relevance of clinically defined HNPCC patients without characteristic...

EDITOR—Hereditary non-polyposis colorectal cancer (HNPCC) is a heterogeneous autosomal dominant disease with incomplete penetrance. The frequency is estimated at 1:200/1:1000. HNPCC results from constitutional mutation in one of the five human mismatch repair genes (MMR) that have so far been implicated: hMSH2, hMLH1, hPMS1, hPMS2, and hMSH6. 2 hMSH2 and hMLH1 account for the majority of mutati...

EDITOR—Hereditary non-polyposis colorectal cancer (HNPCC) is a heterogeneous autosomal dominant disease with incomplete penetrance. The frequency is estimated at 1:200/1:1000. HNPCC results from constitutional mutation in one of the five human mismatch repair genes (MMR) that have so far been implicated: hMSH2, hMLH1, hPMS1, hPMS2, and hMSH6. 2 hMSH2 and hMLH1 account for the majority of mutati...

conclusions the results of this study indicated that patients with sepsis had lower serum vitamin d levels than healthy controls. also, patients with more severe disease had lower serum vitamin d levels, but to evaluate causation and determine whether vitamin d supplementation could be effective in reducing the risk or severity of sepsis, randomized controlled trials should be conducted. result...

EDITOR—Hereditary non-polyposis colorectal cancer (HNPCC) is a heterogeneous autosomal dominant disease with incomplete penetrance. The frequency is estimated at 1:200/1:1000. HNPCC results from constitutional mutation in one of the five human mismatch repair genes (MMR) that have so far been implicated: hMSH2, hMLH1, hPMS1, hPMS2, and hMSH6. 2 hMSH2 and hMLH1 account for the majority of mutati...

EDITOR—Hereditary non-polyposis colorectal cancer (HNPCC) is a heterogeneous autosomal dominant disease with incomplete penetrance. The frequency is estimated at 1:200/1:1000. HNPCC results from constitutional mutation in one of the five human mismatch repair genes (MMR) that have so far been implicated: hMSH2, hMLH1, hPMS1, hPMS2, and hMSH6. 2 hMSH2 and hMLH1 account for the majority of mutati...

Correlation of postmortem anatomic findings with electrocardiographic changes in patients with myocardial infarction. Circulation 55: 279, 1977 23. Starr JW, Wagner GS, Draffin RM, Reed JB, Behar VS: Vectorcardiographic criteria for the diagnosis of anterior myocardial infarction, Circulation 53: 229, 1976 24. Fenoglio JJ, Sylva FG, Freidman PL, Wit AL: Survival of subendocardial Purkinje fiber...

Correlation of postmortem anatomic findings with electrocardiographic changes in patients with myocardial infarction. Circulation 55: 279, 1977 23. Starr JW, Wagner GS, Draffin RM, Reed JB, Behar VS: Vectorcardiographic criteria for the diagnosis of anterior myocardial infarction, Circulation 53: 229, 1976 24. Fenoglio JJ, Sylva FG, Freidman PL, Wit AL: Survival of subendocardial Purkinje fiber...