نتایج جستجو برای: and ascorbate

تعداد نتایج: 16827872  

Journal: :The Biochemical journal 2010
Darius J R Lane Stephen R Robinson Hania Czerwinska Glenda M Bishop Alfons Lawen

Astrocytes are central to iron and ascorbate homoeostasis within the brain. Although NTBI (non-transferrin-bound iron) may be a major form of iron imported by astrocytes in vivo, the mechanisms responsible remain unclear. The present study examines NTBI uptake by cultured astrocytes and the involvement of ascorbate and DMT1 (divalent metal transporter 1). We demonstrate that iron accumulation b...

2018

Ascorbate, as a strong and active antioxidant, plays an important role in keeping human health. It helps promote iron absorption, increase antibody concentration and improve human immunity. Ascorbate is used to regenerate a-tocopherol (vitamin E), and remove radicals which could induce cancer and senescence. Ascorbate is beneficial to strengthen blood vessel and decrease cholesterol concentrati...

2017

Ascorbate, as a strong and active antioxidant, plays an important role in keeping human health. It helps promote iron absorption, increase antibody concentration and improve human immunity. Ascorbate is used to regenerate a-tocopherol (vitamin E), and remove radicals which could induce cancer and senescence. Ascorbate is beneficial to strengthen blood vessel and decrease cholesterol concentrati...

Journal: :The Biochemical journal 1997
H M Jespersen I V Kjaersgård L Ostergaard K G Welinder

Ascorbate peroxidases are haem proteins that efficiently scavenge H2O2 in the cytosol and chloroplasts of plants. Database analyses retrieved 52 expressed sequence tags coding for Arabidopsis thaliana ascorbate peroxidases. Complete sequencing of non-redundant clones revealed three novel types in addition to the two cytosol types described previously in Arabidopsis. Analysis of sequence data av...

Journal: :FEBS letters 2001
M M VanDuijn J Van der Zee P J Van den Broek

Erythrocytes can reduce extracellular ascorbate free radicals by a plasma membrane redox system using intracellular ascorbate as an electron donor. In order to test whether the redox system has electrogenic properties, we studied the effect of ascorbate free radical reduction on the membrane potential of the cells using the fluorescent dye 3,3'-dipropylthiadicarbocyanine iodide. It was found th...

Journal: :National journal of community medicine 2023

Background: Anaemia has significant impact on health of the fetus as well that mother. Increased need iron during pregnancy especially after 2nd trimester makes supplementation mandatory. Ferrous ascorbate is known to exist intact inside gastrointestinal tract due stable chelation with ascorbate. This compound does not dissociate any food inhibitors. The aim study effectiveness Ascorbate and su...

2018
Yun-Xin Lu Qi-Nian Wu Dong-liang Chen Le-Zong Chen Zi-Xian Wang Chao Ren Hai-yu Mo Ya Chen Hui Sheng Ying-Nan Wang Yun Wang Jia-Huan Lu De-shen Wang Zhao-lei Zeng Feng Wang Feng-Hua Wang Yu-Hong Li Huai-Qiang Ju Rui-Hua Xu

Rationale: The antitumor activity of high-dose ascorbate has been re-evaluated recently, but the mechanism underlying cell-specific sensitivity to ascorbate has not yet been clarified. Methods: The effects of high-dose ascorbate on gastric cancer were assessed using cancer cell lines with high and low expression of GLUT1 via flow cytometry and colony formation assays in vitro and patient-derive...

Journal: :Investigative ophthalmology & visual science 1981
R R Pfister S A Hayes C A Paterson

Rabbits receiving subcutaneous ascorbate after corneal wounding showed significant elevation of aqueous humor ascorbate levels but no enhancement of wound breaking strength when compared to controls. In a second group of rabbits, perilimbal alkali burning reduced aqueous humor ascorbate levels one-half to one-third normal. In these perilimbally burned eyes with wounds in clear cornea, subcutane...

2007
JOSEPH J. BARYCKI

2.1. Glutathione 2.1.A. Biological Functions 2.1.B. Biosynthesis 2.1.C. Degradation 2.1.D. Other Thiol-Based Redox Buffers 2.2. Ascorbate 2.2.A. Ascorbate Chemistry 2.2.B. Ascorbate Biosynthesis 2.2.C. Ascorbate Recycling 2.2.D. Ascorbate Transport 2.2.E. Importance of Ascorbate in Stress and Disease 2.3. Other Antioxidants 2.3.A. Lipid-Soluble Antioxidants 2.3.B. Water-Soluble Antioxidants 2.3...

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