The transcription repressor Tramtrack (TTK) is found in cone cells but not photoreceptor cells of the Drosophila eye. We show that down-regulation of TTK expression occurs in photoreceptor cells and is required for their fate determination. Down-regulation requires the presence of Phyllopod (PHYL), which is induced by the RAS pathway, and Seven In Absentia (SINA). Loss of either gene causes acc...

BACKGROUND Neuronavigation is an established technology in neurosurgery. In parts of the world and certain circumstances in which neuronavigation is not easily available or affordable, alternative techniques may be considered. OBJECTIVE An app to assist scalp localization of superficial supratentorial lesions has been introduced, and its accuracy has been compared with established neuronaviga...

There has been a tremendous rise in the growth of online social networks all over the world in recent years. This has facilitated users to generate a large amount of real-time content at an incessant rate, all competing with each other to attract enough attention and become trends. While Western online social networks such as Twitter have been well studied, characteristics of the popular Chines...

Ibn Sina is regarded as one of the greatest physicians, thinkers and medical scholars in the history of medicine. Ibn Sina, a Persian scholar in the medieval era, wrote a famous book of medicine, the Canon of Medicine. The book was adopted as the main textbook of medicine in most Western and Persian universities. In the present critique, we analyzed the functional and anatomic descriptions of t...

background: agility means ability to respond and react quickly and successfully to environmental changes. agility is an important factor for hospital effectiveness. agility in a hospital indicates the hospital's responsiveness when faced with internal and external changes. if hospitals are designed to be agile, they should have the ability to compete with other hospitals and provide appropriate...

We have examined the roles played by the Drosophila neural RNA-binding protein Musashi (MSI) in eye development. MSI expression was observed in the nuclei of all photoreceptor cells (R1-R8). Although a msi loss-of-function mutation resulted in only weak abnormalities in photoreceptor differentiation, we found that the msi eye phenotype was significantly enhanced in a seven in absentia (sina) ba...