The goal was to identify sound pressure level (SPL) at the neonatal intensive care unit (NICU) and inside the incubator of a teaching hospital of a public university from São Paulo - SP, Brazil. SPL inside the NICU and the incubator were measured using four dosimeters in January/2010. SPL at the NICU varied from 52.6 dBA to 80.4 dBA and inside the incubator, from 45.4 dBA to 79.1 dBA. SPL both ...

Drosophila atonal (ato) is required for the specification of founding R8 photoreceptors during retinal development. ato is regulated via dual eye-specific enhancers; ato-3' is subject to initial induction whereas 5'-ato facilitates Notch-mediated autoregulation. Notch is further utilized to induce bHLH repressors of the E(spl) locus to restrict Ato from its initial broad expression to individua...

A dramatic example of a phenotypic interaction that involves neurogenic loci during Drosophila imaginal development is the synergistic impact of split (spl), a recessive allele of the Notch locus, and E(spl)D, a dominant gain-of-function allele of the Enhancer of split locus, on morphogenesis of the compound eye. Screens for mutations that relieve the enhancing effect of E(spl)D on spl have yie...

This paper examines possibilities and consequences of introducing variability with respect to pricing, accounting, and way of payment into software product lines for developers, vendors, and customers. The global goal is the derivation of an extensible conceptual framework for vendors of SPLs which adds relevant economic variability to the SPL. The capability of economic methods for pricing and...

The software product line (SPL) community defines SPLs not only by technical aspects like configurability and code reuse among product line variants, but also by the engineering process that accompanies the development. This paper discusses the question whether this engineering process is a mandatory property of SPLs; it concretely examines the Linux Kernel, which is not being developed accordi...

Techniques to model software product lines (SPLs), using feature models, usually focus on a single SPL. Larger SPLs can also be built from smaller SPLs which results in a dependency between the involved SPLs, i.e., one SPL uses functionality provided by another SPL. Currently, this can be described using constraints between the involved feature models. However, if multiple differently configure...

The SQUAMOSA PROMOTER BINDING PROTEIN-LIKE (SPL) gene family is an SBP-box transcription family in Arabidopsis. While several physiological responses to SPL genes have been reported, their biological role remains elusive. Here, we use a combined analysis of expression correlation, the interactome, and promoter content to infer the biological role of the SPL genes in Arabidopsis thaliana. Analys...

Abstract Background The aim of this study was to clarify the differences in morphological features between long plantar ligament (LPL) and short (SPL). Methods This investigation examined 50 legs from 25 Japanese cadavers. LPL SPL each leg were classified into one three types based on shape number fiber bundles. Then, bundle length, width, thickness measured. Results rectangular (Type I) 12%, h...

Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid involved in immunity, inflammation, angiogenesis, and cancer. S1P lyase (SPL) is the essential enzyme responsible for S1P degradation. SPL augments apoptosis and is down-regulated in cancer. SPL generates a S1P chemical gradient that promotes lymphocyte trafficking and as such is being targeted to treat autoimmune diseases. Despite growi...