Introduction: Anethole is the main constituent of Pimpinella anisum L. (anise), a herbaceous annual plant which has several therapeutic effects. In the folk medicine, anise is employed as an antiepileptic drug. Specifically, this study was focused on the cellular effect of anethole, an aromatic compound in essential oils from anise and camphor. Anethole has various physiological effects on t...

Use of natural compounds as antivirulence drugs could be an alternative therapeutic approach to modify the outcome of bacterial infections, particularly in view of growing resistance to available antimicrobials. Here, we show that sub-bactericidal concentration of anethole, a component of sweet fennel seed, could suppress virulence potential in O1 El Tor biotype strains of toxigenic Vibrio chol...

introduction: anethole is the main constituent of pimpinella anisum l. (anise), a herbaceous annual plant which has several therapeutic effects. in the folk medicine, anise is employed as an antiepileptic drug. specifically, this study was focused on the cellular effect of anethole, an aromatic compound in essential oils from anise and camphor. anethole has various physiological effects on the ...

Several naturally occurring essential oils including carvacrol, anethole, cinnamaldehyde, cinnamic acid, perillaldehyde, linalool, and p-cymene were evaluated for their effectiveness in reducing decay and increasing antioxidant levels and activities in 'Duke' blueberries ( Vaccinium corymbosum). Carvacrol, anethole, and perillaldehyde showed the capability to promote total anthocyanins and tota...

It has been reported that several naturally occurring and related syn thetic organosulfur compounds exert chemopreventive effects in several target organs in rodent models. The chemopreventive actions of 40 and 80% maximum tolerated doses (MTD) of organosulfur compounds, namely anethole trithione, diali) I disulfide, W-acelylcysteine, and taurine, administered in AIN-76A diet, on azoxymethane (...

In recent years there has been an increasing search for new antifungal compounds due to the side effects of conventional antifungal drugs and fungal resistance. The aims of this study were to test in vitro the activity of thymol, eugenol, estragole and anethole and some O-methyl-derivatives (methylthymol and methyleugenol) against Candida spp. and Microsporum canis. The broth microdilution meth...

The purpose of this study, which comprised 2 experiments, was to investigate cognitive effects on odor perception. An odor was presented using an olfactometer. In Experiment 1 ("continuous" presentation), anethole, an odor unfamiliar to most Japanese individuals, was presented continuously for 1 session (20 min), whereas in Experiment 2 ("intermittent" presentation), odor stimuli were presented...

In the present study Willbutrin (bupropion hydrochloride) was employed to induce mutagenic/ carcinogenic features in mice, i.e. undesirable cell division and DNA damage. The repair actions of fennel dry seeds and its extracted bioactive substance anethole supplied to Willbutrin-treatedmice in a dietary regime were investigated. Male Swiss albino mice (25-30gm) orally received Willbutrin dose (0...

Photo-oxygenation of trans anethole (1), the main constituent of anise essential oil, using tetraphenylporphyrine (TPP) as a singlet oxygen sensitizer in chloroform gave 4-methoxybenzaldehyde (p-anisaldhyde) (2), 2-(4-methoxyphenyl)propan-2-ol (3) as well as erythro and threo 1-(4-methoxyphenyl)propane-1,2-diol (4a, 4b). The structures of the photo-oxygenation products were elucidated by spectr...