angiotensin-ii is a multifunctional hormone that regulates blood pressure, plasma volume, neuronal functions, electrolyte balance, thrust and various other vital mechanisms. it acts through its receptors at 1 and at 2 . the involvement of angiotensin-ii and its receptors in cognition is still ambiguous. therefore, the present study was designed to investigate the effect of angiotensin-ii (2 μg/...

Critically ill #COVID19 patients display markedly increased alternative angiotensin pathway activity compared to healthy controls, reflected by blood ACE2 levels as well decreased angiotensin-II and enhanced angiotensin-1–7 formationhttps://bit.ly/2MU1z4z

angiotensin i-converting enzyme (ace) gene polymorphism; genotype dd or d allele may be involved with an increased susceptibility to type 2 diabetes and diabetic nephropathy (dn). we examined the frequency of ace gene polymorphism in 170 patients (85 type 2 diabetes with nephropathy and 85 without it) in tehran, iran. dna was extracted from the white blood cells and the i/d polymorphism of the ...

background: angiotensin i converting enzyme (ace) is a zinc metalloproteinase, converts ang-i to ang- ii, a pro-inflammatory agent which may contribute to pathophysiology of some diseases like type 2 diabetes. objective: to investigate the relationship between ace i/d polymorphism and type 2 diabetes in 261 iranian casecontrol pairs. methods: 170 patients (85 type 2 diabetics with nephropathy a...

background: sarcoidosis is a multisystem inflammatory disease of unknown origin with characterization of small granulomas. angiotensin-converting enzyme (ace) is a pathophysiologic marker of sarcoidosis. we present the ace insertion/deletion (i/d) polymorphism in correlation with serum ace level in iranian patients with sarcoidosis. methods: from jan 2014 to jan 2015, 102 iranian patients who h...

background: antispasmodic and vasorelaxant effects of teucrium polium l . (tp) were mentioned in former studies, so we attempted to evaluate the eventual preventive effect of tp in an acute experimental model of hypertension induced by angiotensin ii (ang ii). methods: forty‑eight male wistar rats were divided randomly into six groups ( n = 8); control group (c), which received only saline, gro...

introduction: in patients with uncomplicated primary hypertension (htn), angiotensin converting enzyme inhibitors (aceis) are considered as monotherapy. in some studies, cough was not related to age, sex, underlying disease, or drug dosage. however, in previous studies, the incidence of cough was greater in females than males. the aim of this study is to determine the incidence of captopril-ind...

angiotensin converting enzyme (ace; omim: 106180) has an important role in the conversion of angiotensin i to angiotensin ii and degradation of bradykinin. genetic polymorphism i/d (rs4646994) in the gene encoding ace has been well defined. to get more insight into the genetic structure of iranian populations, the distribution of the ace i/d polymorphism among iranians was compared with each ot...