background: erythropoietin (epo) was first known as a factor for red blood cell proliferation and differentiation. new studies show the effects of epo on immune system. objective: in this study, the effects of pretreatment with recombinant human erythropoietin (rhuepo) on the anti-human leukocyte antibody (anti-hla) titer were determined. methods: three groups of rats were sensitized with human...

purpose: to evaluate the vascular occlusion in coats’ disease   methods: in this non-comparative case series, 13 consecutive patients with coats’ disease from january 2011 to september 2011 were included. the hypercoagulability states were evaluated in these patients.   results: the mean age of the patients in this series was 15.4 years. all but one patient had high anti-cytomegalovirus antibod...

BACKGROUND: BACKGROUND: Enterotoxigenic Escherichia coli (ETEC) is the main causative agents of neonatal calf diarrhea. Passive transfer of antibodies that is derived from the dams of the calves through their colostrum plays an important role in disease prevention. OBJECTIVES: To determine the presence of natural specific antibodies against K99 antigen in dam’s serum and colostrum as well as in...

Chemical immunotherapeutic strategies including Antibody Recruiting Molecules (ARMs - bivalent small molecules containing an antibody-binding domain (ABD) and a target-binding (TBD)) direct immune-mediated clearance of diseased cells. Anti-cancer ARM function relies on high tumor antigen valency, limiting against lower expressing tumors. To address this limitation, we report tunable multivalent...

Background: Helicobacter pylori infection is one of the most common gastrointestinal infections worldwide. Predominant T-helper 1 (Th1) responses with increased gamma interferon (IFN- γ) levels have been proposed to play an important role in H. pylori-induced peptic ulcer. However, bacterial factors contributing to the initiation of Th1 polarization of H. pylori-specific immune responses have n...

background: preeclampsia (pe) is a pregnancy specific syndrome that is associated with high maternal and fetal morbidity and mortality. glucose regulated protein78 (grp78) is an endoplasmic reticulum (er) protein which is expressed on the cell surfaces of trophoblast cells under stress or hypoxic condition. grp78 has a role in aggressive behavior of invasive cells and may play a role in normal ...

background: cryptosporidium parvum is a parasitic protozoan that functions as important causa­tive agent of diarrhea in human and animals. the host's immune response to surface anti­gens of c. parvum has been previously demonstrated. in this respect, the role of humoral immu­nity in the development of host protective immunity against this protozoon has been well demon­strated. methods: the effe...

Abstract Maternal and cord blood sera were collected from 20 parturients who received the BNT162b2 vaccine. All women infants positive for anti S- anti-receptor binding domain antibody–specific immunoglobulin G. Cord antibody concentrations correlated to maternal levels time since vaccination. Antenatal severe acute respiratory syndrome coronavirus 2 vaccination may provide neonatal protection.

Objective(s): Enterotoxigenic Escherichia coli (ETEC) strains are one of the primary causes of diarrhea in newborn calves and in humans, pigs, and sheep. IgY technology has been identified as a promising alternative to generating a mass amount of specific antibody for use in immunotherapy and immunodiagnostics. The purpose of this study was to produce specific antibody by egg yolk antibody (IgY...