Objectives: The aim of the study was to evaluate outcome pregnancy and early development offspring, in women with epilepsy (WWE) who were receiving not anti-epileptic drugs (AED). Methods: Women delivered a teaching hospital (n=60), between November 2017 October 2018, identified from delivery records (n=5202) their infants (n=39) underwent developmental assessment by Baroda screening test. Mate...

Epilepsy is a frequent condition in the elderly; however, it remains a relatively understudied condition in older adults with dementia. The diagnosis of a seizure is particularly difficult and is most often based on questions to the caregiver. Epilepsy in dementia has significant consequences on the prognosis of the underlying dementia: it can result in a worsening of cognitive performance, par...

Mechanisms responsible for the attention impairment in epileptics may be different from those involved in isolated AttentionDeficit-Hyperactivity Disorder (ADHD) [1]. Often a combination of anti-epileptic drugs (AEDs) used in combinations are required for intractable epilepsy, but this can also exacerbate drug-induced side effects such as slowed cognition and sedation [2]. Symptoms of inattenti...

A delayed diagnosis of insulinoma remains a clinical issue. Hypoglycemic symptoms can mimic neuropsychiatric disorders such as epilepsy. A 27-year-old woman with a history of epilepsy and anti-epileptic drugs (AEDs) developed repeated seizures and neuropsychiatric symptoms after a 9-year asymptomatic interval. She had received transient treatment with AEDs before the possibility of hypoglycemia...

Increased asymmetric dimethylarginine level after antiepi-leptic drug treatment may be independent of the changes in plasma homocysteine level Dear Editor, We have read the recent article by Sniezawska and colleagues with great interest. 1 The authors investigated the frequency of polymorphism in the MTHFR (C677T), MTR (A2756G), and MTHFD1 (G1958A) genes and analysed the levels of homocysteine ...

A wind of change characterizes epilepsy research efforts. The traditional approach, based on a neurocentric view of seizure generation, promoted understanding of the neuronal mechanisms of seizures; this resulted in the development of potent anti-epileptic drugs (AEDs). The fact that a significant number of individuals with epilepsy still fail to respond to available AEDs restates the need for ...

PURPOSE Various factors may affect intrauterine foetal growth, amongst which conditions such as epilepsy and the use of anti-epileptic drugs (AED) may play a role. This study investigated intrauterine growth of foetuses in women with epilepsy, as compared with controls, and explored whether intrauterine growth was affected by prenatal exposure to AED. METHOD Data were obtained from prospectiv...

UNLABELLED Epilepsy is very prevalent among elderly inpatients and treatment is far from ideal. OBJECTIVE To analyze prescribing patterns of antiepileptic drugs (AEDs) for hospitalized elderly with epilepsy, their relations with comorbidities and comedications. METHOD We assessed prescription regimen of elderly patients that were under AED use for treatment of epileptic seizures, during hos...

NEED AND PURPOSE OF REVIEW A number of newer anti-epileptic drugs have been developed in the last few years to improve the treatment outcomes in epilepsy. In this review, we discuss the use of newer anti-epileptic drugs in children. METHODS USED FOR LOCATING, SELECTING, EXTRACTING AND SYNTHESIZING DATA MEDLINE search (1966-2013) was performed using terms newer anti-epileptic drugs, Oxcarbazep...

Epilepsy represents the most common serious neurological disorder, with a prevalence of 0.4 - 1%. Approximately 30% of patients are resistant to currently available drugs. New anti-epileptic drugs are needed to treat refractory epilepsy, improve upon current therapies, improve the prognosis of epilepsy and to prevent the epileptogenic process. Designing compounds with specific physiological tar...