BACKGROUND AND AIMS The involvement of thyroid autoimmunity and dysfunction in patients with chronic hepatitis C virus (HCV) infection before interferon-α (IFN-α) therapy remains controversial. We performed this meta-analysis to evaluate the association of HCV infection with the presence of anti-thyroid antibodies and dysthyroidism. METHODS A literature search was carried out to collect artic...

Objective: To evaluate hepatitis B and C serology findings to determine the current prevalence of those who had applied Turkish hospital in Mogadishu, Somalia. Material Method : The demographic test results (HBsAg, antiHBs antibody, anti-HCV) patients were recorded retrospectively from their files. Results: A total 152,266 patients, 75,903 (49.8%) male 76,363 (50.2%) female, with a mean age 34 ...

BACKGROUND All donated blood in Israel is tested for anti-hepatitis C virus (HCV) antibodies by enzyme immunoassay (EIA) and donors are notified of the result. There is evidence that at low antibody titres, the percentage of false positives may be high, with consequent labelling of healthy people as being infected with HCV. AIM In this study we examined the correlation between anti-HCV antibo...

BACKGROUND It has been proposed that hepatitis C virus (HCV)-infected patients with end-stage renal disease undergoing maintenance haemodialysis may lack HCV antibody (anti-HCV) despite chronic HCV viraemia. This carries important implications for the design of surveillance policies. METHODS To characterize the prevalence of antibody-negative/RNA-positive HCV infection, patients attending sev...

Background and Aims: Many studies have provided evidence for the role of hepatitis B and C viruses in the development of liver cancer. Although the routine treatment is available for both conditions, no definite guideline is available to treat patients dually infected with HBV and HCV. This study was performed to determine the frequency of HBV/HCV-coinfection in Mashhad, North-East of Iran. Mat...

background: in spite of available, and sensitive screening assay for detection of hepatitis b virus surface antigen (hbsag), occasional cases of post-transfusion hepatitis b virus infection are still observed. the aim of the present study was to assess the prevalence of positive anti hepatitis b core (anti-hbc) and presence of hbv-dna in serum sample of healthy blood donors negative for both hb...

Hepatitis C virus (HCV) often causes persistent infection despite the presence of neutralizing antibodies against the virus in the sera of hepatitis C patients. HCV infects both hepatocytes and B cells through the binding of its envelope glycoprotein E2 to CD81, the putative viral receptor. Previously, we have shown that E2-CD81 interaction induces hypermutation of heavy-chain immunoglobulin (V...

Anti-HCV antibody was detected in 1.9% of the blood donors in University Hospital. Among the risk groups, 33.3% of the patients with post-transfusion hepatitis were tested positive for anti-HCV antibody. The anti-HCV antibody was detected in 30% of the IDU. Haemodialysis patients, patients with acute and chronic hepatitis and patients with liver cirrhosis appeared to have increased risk of Hepa...

results the mean age of children was 6.5 ± 4.2 years. the frequency of positive results for hbsag, anti-hbs and anti-hcv in all age groups were 12 (3.6%), 47 (14.2%) and 2 (0.6%), respectively. anti-hiv was not detected in any of the children's serum samples. the frequency of positive results for hbsag was significantly higher in children older than six years than in other age groups. conclusio...

BACKGROUND Porto Alegre is the Brazilian state capital with second highest incidence of tuberculosis (TB) and the highest proportion of people infected with human immunodeficiency virus (HIV) among patients with TB. Hepatitis C virus (HCV) infection increases the risk of anti-TB drug-induced hepatotoxicity, which may result in discontinuation of the therapy. OBJECTIVES The aim of this study w...