Background: In this study, we evaluated antibacterial and antifungle activity of these derivatives against gram positive (Staphylococcus aureus, Bacillus subtilis, B. cereus), gram negative (Proteus vulgaris) bacteria and fungale (Candida albicans, C. tropicalis and C. glabrata). Methods: The broth macro dilution and well agar diffusion methods were used for determination of inhibition zoom (I...

The in vitro antibacterial and antifungal activities of demethoxyviridin and some synthetic analogues were evaluated by the agar diffusion method. The minimum inhibitory concentrations (MIC) of the active compounds were also determined by the agar dilution method. Demethoxyviridin (1) showed moderate antibacterial activity against most of the strains tested. 1alpha-Hydroxydemethoxyviridin (3) s...

Introduction: Natural products have been the most successful source of potential drug leads. One of them is lichens, which have been used since antiquity as natural sources of drugs. The aim of this study was to investigate the antibacterial and antifungal activity of different extracts of the Iranian lichens in Ilam Province. Methods: The aqueous, acetone, and methanol extracts of 6 lichen spe...

Nepeta depauperata belongs to the Lamiaceae family and is one the Persian endemic plants which has not been investigated biologically. In the present paper we had focused on the assessment of the antibacterial and antifungal activities of the total methanolic extract and different sub-fraction of the flowering aerial parts of it. The Antibacterial and antifungal activities were investi...

Andrographis alata Nees is an important medicinal plant. The current study was to investigate the antibacterial, antifungal activity and phytochemical analysis of the various leaf and stem extracts of A.alata. Methanol, ethanol, chloroform, acetone and petroleum ether extracts of shade dried plant leaf and stem of A.alata were tested for antibacterial, antifungal and phytochemical screening. Th...

Fractions obtained from partitioning of aerial methanolic extract of Euphorbia Aellenii with chloroform (E2), ethyl acetate (E3), n-butanol (E4) and water (E5) were investigated in vitro for their phytotoxicity, insecticidal, anti-leishmanial, cytotoxicity, antibacterial and antifungal activities. Sample E2 appeared to have significant phytotoxic activity. In the insecticidal screening study o...

sponges are the simplest multicellular animals that lack defense mechanisms and rely on chemical defense  that have been used by mankind to develop antimicrobial drugs against diseases.  the present study was designed to demonstrate the antibacterial and antifungal activities of marine sponge dysidea pallescens semipolar and nonpolar extracts. in this study, d. pallescens were collected from he...

Brown alga, Turbinaria conoides was successively extracted with n-hexane, cyclohexane, methanol and ethanol:water (1:1). The extracts were evaluated for antibacterial and antifungal activities by disc diffusion method. Minimal inhibitory concentration was determined for active extracts by broth dilution method. The antiviral activity and cytotoxicity of the extracts were tested in human embryon...

This paper reviews 116 new compounds with antifungal or antibacterial activities as well as 169 other known antimicrobial compounds, with a specific focus on January 2010 through March 2015. Furthermore, the phylogeny of the fungi producing these antibacterial or antifungal compounds was analyzed. The new methods used to isolate marine fungi that possess antibacterial or antifungal activities a...

Brown alga, Turbinaria conoides was successively extracted with n-hexane, cyclohexane, methanol and ethanol:water (1:1). The extracts were evaluated for antibacterial and antifungal activities by disc diffusion method. Minimal inhibitory concentration was determined for active extracts by broth dilution method. The antiviral activity and cytotoxicity of the extracts were tested in human embryon...