Fifty six children with thalassaemia, and 118 healthy subjects, who had all been immunised with an intramuscular injection of hepatitis B vaccine (HB-VAX) into the deltoid area three years previously, were given booster doses intradermally. All responders (good = hepatitis B surface (HBs) antibody titre greater than or equal to 10 U/l; poor = HBs antibody titre less than 10 U/l) showed pronounc...

  Humoral immune response of vaccine-I (supermatent from sonicated sporulated oocyst), vaccine –II (sediment from sonicated sporulated oocyst) and vaccine –III (un-sonicated sporulated oocyst) against conccidiosis in chickens was determined by indirect haemagglutination (IHA) test. IHA antibody titre was significantly higher (p

Avian influenza (AI) H9N2 has been reported from poultry in India. A seroepidemiological study was undertaken among poultry workers to understand the prevalence of antibodies against AI H9N2 in Pune, Maharashtra, India. A total of 338 poultry workers were sampled. Serum samples were tested for presence of antibodies against AI H9N2 virus by hemagglutination inhibition (HI) and microneutralizati...

Immune suppression resulting from chemoprophylaxis and potential drug interaction were investigated in experimental animals pre-medicated with ampicillin and chloroquine followed by immunization with bovine serum albumin bearing liposomes prepared by the reverse phase evaporation method. The prepared liposomes were evaluated for particle size, entrapment efficiency and in vitro release. Humoral...

BACKGROUND Severe respiratory syncytial virus (RSV) disease occurs predominantly in children under 6 months of age. There is no licensed RSV vaccine. Protection of young infants could be achieved by a maternal vaccine to boost titres of passively transferred protective antibodies. Data on the level and kinetics of functional RSV-specific antibody at birth and over the early infant period would ...

The time course of DNA binding capacity (DNA-bc) was found to correlate with the clinical course in a group of 21 patients who had biopsy-proven lupus glomerulonephritis and were treated with immunosuppressive agents. Eight patients showed a sequential DNA-bc pattern in which a high titre of anti-DNA antibody was present for a prolonged period of time all having an unfavourable clinical course....

Three hundred and twenty four serum samples, collected from different areas of Punjab, NWFP and Azad Kashmir, were screened for Toxo IgG and IgM antibody titres utilizing the Enzyme linked immunosorbent assay (ELISA). Of the total 149 (46%) samples were positive for IgG antibody. Seven (2.1%) showed titre greater than 130. Ninety sera (27.7%) were positive for IgM antibody, twenty six (8%) had ...

OBJECTIVES To investigate the effect of Chlamydia pneumoniae infection on future development of ischaemic heart disease and mortality. DESIGN Prospective longitudinal study. SETTING Caerphilly, South Wales. SUBJECTS Plasma specimens were collected during 1979-83 from 1773 men aged 45-59 years. These were tested for IgG and IgA antibodies to C pneumoniae (TW183) by microimmunofluorescence....

Immune complexes, human erythrocytes coated with human IgG antibody, inhibit the migration of lymphocytes from rheumatoid arthritis (RA) patients. No correlation could be observed between migration inhibition and Waaler-Rose titre (sheep cell agglutination titre) in inidvidual patients. Production of migration inhibitory factor (MIF) could be detected in 16 of 20 cultures of RA lymphocytes incu...

humoral immune response of vaccine-i (supermatent from sonicated sporulated oocyst), vaccine –ii (sediment from sonicated sporulated oocyst) and vaccine –iii (un-sonicated sporulated oocyst) against conccidiosis in chickens was determined by indirect haemagglutination (iha) test. iha antibody titre was significantly higher (p