The use of nitrogen mustards as chemotherapeutic agents in the treatment of certain neoplastic diseases has been well established by a large number of workers (Montgomery, 1959; Creech, Breuninger, Hankwitz, Polsky & Wilson, 1960; Ross, 1962). A large number of different compounds have been screened in various test systems in vitro and in vivo for anticancerous, antibacterial, antimicrobial and...

'Krishna Jeerakam' is a small black seed which is used in the preparation of certain Ayurvedic medicines. The terms 'Karavi', 'Prithvi' and 'Kala' are used frequently as its synonyms. Each word conveys a specific meaning which indicates one or other property of the drug. 'Karavi' means savior from the fear of death and 'prithvi' conveys the meaning 'famous' and kala emphasizes the black colour ...

Bromelain belongs to a group of protein digesting enzymes obtained commercially from the fruit or stem of pineapple. Fruit bromelain and stem bromelainare prepared differently and they contain different enzymatic composition. "Bromelain" refers usually to the "stem bromelain." Bromelain is a mixture of different thiol endopeptidases and other components like phosphatase, glucosidase, peroxidase...

Podophyllum hexandrum Royle syn P. emodi Wall. ex Hook.f. & Thoms. is an endangered and valuable medicinal plant, distributed in the Himalayan zone at an altitudes ranging from 2000 to 4000 m above MSL. It is an herbaceous and rhizomatous perennial plant also found in few pockets of Indian cold desert (Ladakh and Lahaul-Spiti). Its rhizomes and roots contain about 8% of podophylloresin from whi...

Human have been constantly using plants and plant products to overcome many diseases. The antioxidant property of the plant sources is studied to obtain an efficacious drug against cancer. The objectives of the present study is to evaluate the antioxidant and cytotoxic activity of the Tecoma stans extracts against lung cancer cell line in comparison with vincristine drug. The antioxidant activi...

Abstract Background Cancer is one of the most critical but ubiquitous causes death grappled from past decades. Widely used chemotherapy with cytotoxic activity blocks/ kills cancer cell. The compounds targeted for anticancerous are either derived synthetically or naturally (through plants microbial origin). Current day, versatile role in medicinal field has been attributed to secondary metaboli...

BACKGROUND Research of natural products from traditionally used medicinal plants to fight against the human ailments is fetching attention of researchers worldwide. Bidens pilosa Linn. var. Radiata (Asteraceae) is well known for its folkloric medicinal use against various diseases from many decades. Mizoram, North East India, has high plant diversity and the use of this plant as herbal medicine...

Tetrahydrocurcumin (THC) is a natural molecule with anticancerous, antioxidant and other beneficial activities. However, its low aqueous solubility leads to poor bioavailability. Sodium caseinate (NaCas) an ideal protein carrier amphiphilic non-toxic properties, which provides new possibility for improving the of THC. In this study, THC loaded nanoparticles ([email protected]) were successfully...