نتایج جستجو برای: antigen 5
تعداد نتایج: 1387736 فیلتر نتایج به سال:
We have previously shown that antigen-induced eosinophil recruitment into the tissue of sensitized mice is mediated by CD4+ T cells and IL-5. To determine whether the induction of oral tolerance down-regulates antigen-induced eosinophil recruitment into the tissue, we studied the effect of oral administration of a protein antigen on antigen-induced eosinophil infiltration in the trachea of sens...
Antigen-induced eosinophil recruitment into the airways of sensitized mice is mediated by CD4(+) T cells and their cytokines, especially IL-5. In this study, we found that the antigen-induced airway eosinophilia was diminished in Stat5a-deficient (Stat5a(-/-)) mice and Stat5b-deficient (Stat5b(-/-)) mice. We also found that antigen-induced CD4(+) T-cell infiltration and IL-5 production in the a...
Sulfated tyrosines at the amino terminus of the principal HIV-1 coreceptor CCR5 play a critical role in its ability to bind the HIV-1 envelope glycoprotein gp120 and mediate HIV-1 infection. Here, we show that a number of human antibodies directed against gp120 are tyrosine sulfated at their antigen binding sites. Like that of CCR5, antibody association with gp120 is dependent on sulfate moieti...
understanding the mechanism of tumor resistance is critical for cancer therapy. in this study, we investigated the effect of carcinoembryonic antigen (cea) overexpression on uv-and 5-fluorouracil (5-fu)-induced apoptosis and autophagy in colorectal cancer cells. we used histone deacetylase (hdac) inhibitor, nab and dna demethylating agent, 5- azacytidine (5-aza) to induce cea expression in ht29...
As the COVID-19 epidemic is still ongoing, a more rapid detection of SARS-CoV-2 infection such as viral antigen-detection needs to be evaluated for early diagnosis disease. Here, we report dynamic changes antigens in nasopharyngeal swabs patients and its association with nucleic acid clearance clinical outcomes. Eighty-five were enrolled antigens, including 57 anti-SARS-CoV-2 antibody negative ...
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