نتایج جستجو برای: antimetastatic

تعداد نتایج: 993  

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2008
Dong Yun Lee Kyeongsoon Park Sang Kyoon Kim Rang-Woon Park Ick Chan Kwon Sang Yoon Kim Youngro Byun

PURPOSE Orally active anticancer drugs have great advantages for the treatment of cancer. Compelling data suggest that heparin exhibits critical antimetastatic effects via interference with P-selectin-mediated cell-cell binding. However, heparin should be given parenterally because it is not orally absorbed. Here, we evaluated the inhibitory effect of orally absorbable heparin derivative (LHD) ...

Journal: :Evidence-Based Complementary and Alternative Medicine 2011

Journal: :Biological and Pharmaceutical Bulletin 2002

Journal: :Cancer research 2008
Minalini Lakshman Li Xu Vijayalakshmi Ananthanarayanan Joshua Cooper Chris H Takimoto Irene Helenowski Jill C Pelling Raymond C Bergan

Dietary genistein has been linked to lower prostate cancer (PCa) mortality. Metastasis is the ultimate cause of death from PCa. Cell detachment and invasion represent early steps in the metastatic cascade. We had shown that genistein inhibits PCa cell detachment and cell invasion in vitro. Genistein-mediated inhibition of activation of focal adhesion kinase (FAK) and of the p38 mitogen-activate...

2008
Minalini Lakshman Li Xu Vijayalakshmi Ananthanarayanan Joshua Cooper Chris H. Takimoto Irene Helenowski Jill C. Pelling Raymond C. Bergan

Dietary genistein has been linked to lower prostate cancer (PCa) mortality. Metastasis is the ultimate cause of death from PCa. Cell detachment and invasion represent early steps in the metastatic cascade. We had shown that genistein inhibits PCa cell detachment and cell invasion in vitro . Genistein-mediated inhibition of activation of focal adhesion kinase (FAK) and of the p38 mitogen-activat...

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