background & aim: when the level of free radicals is increased and also when both the enzymatic systems and low molecular antioxidants are not sufficient to protect the organism, it seems necessary to get antioxidants from external sources. this study aimed to evaluate the antioxidant potential of different parts of catharantus roseus experimental: the antioxidant potential of ethanol extra...

The effects of acute exposure to cadmium (Cd) on the blood antioxidant defense system, lipid peroxide concentration and hematological parameters, as well as the possible protective role of vitamin E were studied. Male Wistar albino rats (3 months old) were treated with cadmium (0.4 mg Cd/kg b.m., i.p., 24 h before the experiment) or with vitamin E + Cd (20 IU Vit E/kg b.m., i.m., 48 h + 0.4 mg ...

The present study was designed to study the influence of Varroa on honey bee Apis mellifera.The antioxidant defense system of the brown eye pupathe infestive stage in the life cycle of the hostwas evaluated. This was manifested as elevated activity of antioxidant defense enzymes, with Superoxide dismutase and Catalase activities being almost two times higher in infested versus noninfested pupae...

The increase in oxygen uptake during intense exercise is associated with an increase in the production of reactive oxygen species, a process known as oxidative stress, which may alter cell contents. To limit the damaging effect of this overload of free radicals, the antioxidant defense system must be effective. The repetition of endurance training stimuli causes adaptations of the antioxidant d...

It has been established that intense physical exercise is associated with an increase in free radical production. Our body has defense system to combat the deleterious effect. But, when the body’s natural defense system against free radicals are overwhelmed, oxidative stress increases. In the present investigation, we studied the effect of vitamin supplementation (composed of 400 IU of vitamin ...

Fluphenazine and perphenazine as a phenothiazine-class antipsychotic drugs are widely used to treat psychoses and schizophrenia, however their use is associated with significant side effects such as extrapyramidal symptoms as well as ocular and skin disorders. The aim of this study was to examine the effect of fluphenazine and perphenazine on cell viability, melanogenesis and antioxidant defens...

Introduction. Inflammation-destructive process, accompanying cellulitis, leads to the disturbances of metabolic processes and an imbalance of the antioxidant defense system. Increased free radical generation and lipid peroxidation has been considered to play an important role in the pathogenesis of cellulitis. Salivary parameters (components) reflect the patients’ metabolic state and have clini...

Constant generation of Reactive oxygen species (ROS) during normal cellular metabolism of an organism is generally balanced by similar rate of consumption by antioxidants. Imbalance between ROS production and antioxidant defense results in increased level of ROS causing oxidative stress which leads to promotion of malignancy. Queuine is a hyper modified base analogue of guanine, found at first ...