نتایج جستجو برای: antiphospholipid
تعداد نتایج: 5075 فیلتر نتایج به سال:
Antiphospholipid syndrome can mimic many diseases, one of which is multiple sclerosis. The article presents the main aspects differential diagnosis antiphospholipid and sclerosis, as well its own clinical case.
Manifestation of chorea in patients with systemic lupus erythematosus (SLE) and antiphospholipid antibody syndrome (APA synd.) is not common. Moreover, primary presentation of the disease with chorea is rare and only few such cases are reported in literature in recent years. We report here the case of a 28 year old woman who was first seen at the age of 10 with clinical manifestations of chorea...
Catastrophic antiphospholipid syndrome (CAPS) is an acutely devastating situation characterized by widespread thrombotic microangiopathy in the presence of elevated titers of antiphospholipid antibodies. We describe a 57-year old woman who underwent liver transplantation for primary sclerosing cholangitis and developed this malignant variant of the antiphospholipid syndrome.
Q fever is a neglected and potentially fatal disease. During acute Q fever, antiphospholipid antibodies are very prevalent and have been associated with fever, thrombocytopenia, acquired heart valve disease, and progression to chronic endocarditis. However, thrombosis, the main clinical criterion of the 2006 updated classification of the antiphospholipid syndrome, has not been assessed in this ...
Blood samples from 65 patients with primary Sjögren's syndrome were evaluated for the presence of antiphospholipid antibodies. Increased levels of antiphospholipid antibodies were found in 13 of 65 (20%) of patients. These antiphospholipid antibodies were predominantly of the IgA isotype, in contrast with the IgG isotype antiphospholipid antibodies found in patients with systemic lupus erythema...
OBJECTIVE The non-criteria neuropsychiatric manifestations of antiphospholipid syndrome include headache, dizziness, vertigo, seizure, depression and psychosis. There were still no objective methods qualified to detect the early central nervous system involvement in non-criteria antiphospholipid syndrome. We evaluated the effectiveness of Tc-99m ECD SPECT in assessing circulatory insufficiency ...
background: anti-phospholipids syndrome (aps) is considered a non inflammatory auto-immune disease with a significant thrombophilic risk with varied clinical manifestations. the purpose of the current study was to investigate the frequency of thrombotic and non-thrombotic events in patients with aps. methods: in this retrospective study, 102 definite aps subjects were recruited (2007-2011) at a...
AIM We audited indications and outcomes of antiphospholipid syndrome (APS) screening in the pregnant population at our centre. METHOD Prospective and observational. All APS test results returned were audited for validity of indication and subsequent outcome. RESULT 24 of a total of 146 (16%) of requests for the antiphospholipid antibodies and lupus anticoagulant were not indicated. Two posi...
The antiphospholipid syndrome is a thrombophilic condition marked by antibodies that recognize anionic phospholipid-protein cofactor complexes. We recently reported that exposure to IgG fractions from antiphospholipid patients reduces the level of annexin-V, a phospholipid-binding anticoagulant protein, on cultured trophoblasts and endothelial cells and accelerates coagulation of plasma exposed...
The mechanism underlying the prothrombotic state that characterizes the primary antiphospholipid syndrome proves to be difficult to define mainly because of the variety of the phospholipid and protein targets of antiphospholipid antibodies that have been described. Much of the debate is related to the use of polyclonal antibodies during the different antiphospholipid assays. To better describe ...
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