background and aims: human adenoviruses can cause a diversity of clinical diseases, but there is no antiviral therapy formally approved by adenovirus infections. thus, antiviral agents derived from medicinal plants which are effective against adenoviruses infections are urgently required. therefore, this research was aimed to evaluate in vitro antiadenovirus activity of pomegranate (punica gran...

objectives: evaluation of therapeutic effects of carum copticum (c. copticum) has been the subject of several studies in recent years. thymol the major component of c. copticum is a widely known anti-microbial agent. in this study, the antibacterial and anti viral activities of essential oil of c. copticum fruit were determined. materials and methods: essential oil of c. copticum was analyzed b...

objective: garlic is a plant has been used as a flavor, and anti-microbial and anti-diarrheal agent. infectious bronchitis virus (ibv) is a coronavirus. the available vaccines against ibv cannot cover new variants. this study evaluated the inhibitory effects of garlic extract on ibv.  materials and methods: the constituents of garlic extract were detected by gas chromatography. this study was d...

background and aims: hepatitis c virus is one of the viral infections transmitted by blood transfusion. patients with thalassaemia frequently need blood transfusion and are in danger of hcv infection. in most cases of infection (85%) the virus evades the immune system and establishes a chronic infection that may lead to cirrhosis and liver carcinoma. liver is the main site of hcv replication hc...

background herpes simplex virus 1 (hsv-1) resistance to drugs and the side effects of drugs have drawn the attention of investigators to herbal plants. objectives the main aim of the current research was to investigate the effects of glycyrrhiza glabra (liquorice root) on hsv-1. one of the objectives of the current research was to determine the efficacy and the effect of the elapsed incubation ...

Background and Aims: Interferon alpha is an effective cytokine in viral infections, where it has various roles in immune function. The use of this antiviral agent in the treatment of viral infections and even cancers is common, although, the beneficial effects of this antiviral agent in high doses can be associated with side effects that limit its use. In this project, we tried to investigate t...

Background and Aims: Lemon Balm L (Lamiaceae) has been used in a variety of practical applications in medical sciences. Its antiviral activity against herpes simplex virus type-1 (HSV-1) was investigated in cell culture. Lemon Balm hydroalcoholic extract was found to be non-toxic to Vero cells up to concentration 800 ug/ml and inhibited the growth and development of HSV-1 in dose-dependent mann...

Background: Antiviral screening of newly isolated or synthesized compounds is an important matter which requires a reliable antiviral test. In order to address this issue, the development of a rapid antiphage test has been conducted. To achieve this goal, the antiphage activity of three antiviral drugs (Acyclovir, Lamivudine and Trifluridin) against phage CP51 which infects Bacillus cereus (ATC...