Background and Aim. Recurrent aphthous stomatitis (RAS) is a common oral mucosal disorder characterized by recurrent, painful oral aphthae. Despite extensive research, the exact etiology of RAS remains elusive. Recently oxidant-antioxidant imbalance of the body has been implicated in the pathogenesis of recurrent aphthous stomatitis. Thus, the aim of the study was to evaluate the enzymatic anti...

OBJECTIVE To construct and optimize a neural network that is capable of predicting the occurrence of recurrent aphthous ulceration (RAU) based on a set of appropriate input data. PARTICIPANTS AND METHODS Artificial neural networks (ANN) software employing genetic algorithms to optimize the architecture neural networks was used. Input and output data of 86 participants (predisposing factors an...

Introduction: Recurrent oral aphthous is one of the most common ulcerative lesions of the oral cavity which no specific treatment has been introduced for it, sofar. Some studies suggest the zinc deficiency as one of the etiologic factors in aphthous ulcers and also in other experimental studies, zinc composition has been effective in aphthous treatment. The aim of this stud was to determinate t...

BACKGROUND Recurrent aphthous stomatitis (RAS) is a common condition that affects approximately 20% of the general population. The ulcers can interfere with speech and eating and cause significant pain and discomfort. This study aimed to evaluate the efficacy of Amlexanox and Adcortyl in the treatment of aphthous ulcers. MATERIAL AND METHODS In this randomized double blind clinical trial with...

Attempts were made to demonstrate herpes simplex virus (HSV) type 1 and type 2, varicella zoster virus (VZV) and cytomegalovirus (CMV) in specimens obtained from aphthous ulceration lesions by the immunofluorescent method using fluorescein-labeled monoclonal antibodies. HSV-1 and VZV were detected in 2 and 4 out of 30 patients, respectively. Although almost all viruses that can infect the oral ...

The release of 51Cr from labelled colon cells was used to assess a possible lymphocytotoxic effect of peripheral blood lymphocytes from patients suffering from recurrent aphthous ulceration. No significant (p > 0.03) difference was observed between the isotope release following incubation with patients' or control lymphocytes. The absence of such a lymphocytotoxic effect, detectable with oral e...