objective(s): apolipoprotein e genotype (apoe) polymorphism affects lipid levels and coronary artery disease (cad) risk. the aim of this study was to study the association of the apolipoprotein e genotypes with coronary artery disease in the iranian population.   materials and methods: the apolipoprotein e genotype in dna samples extracted from 66 cad+ patients and 61 control subjects by restri...

Background: Familial chylomicronemia syndrome is a rare disorder of lipoprotein metabolism due to familial lipoprotein lipase or apolipoprotein C-II deficiency or the presence of inhibitors to lipoprotein lipase. It manifests as eruptive xanthomas, acute pancreatitis, and lipaemic plasma due to marked elevation of triglyceride and chylomicrons levels. Case presentation: We report a rare case of...

abstract   background: recently, small dense low density lipoprotein (sdldl) has been highlighted as a new risk factor for the coronary artery disease (cad).small dense ldls are believed to be atherogenic since these particles are taken up more easily by arterial wall. they are readily oxidized and have reduced affinity for low density lipoprotein (ldl) receptor and increased affinity for arter...

background: apolipoprotein a2 (apoa2) is the second major apolipoprotein of the high-density lipoprotein cholesterol (hdl-c). the study aim was to identify apoa2 gene variation in individuals within two extreme tails of hdl-c levels and its relationship with hdl-c level. methods: this cross-sectional survey was conducted on participants from tehran glucose and lipid study (tlgs) at research ins...

objective(s) the sst-i polymorphic site on the 3' untranslated region of the apo ciii gene, has been previously reported to be associated with hypertriglyceridemia. the aim of the present study was to explore the association between sst-i polymorphism with plasma lipid and lipoprotein levels in hyperlipidemic (hlp) patients from semnan province, iran. materials and methods genomic dna was ...

sumac (rhus coriaria l.) is used as an herbal remedy in traditional medicine. the aim of this study was to determine the effects of sumac (rhus coriaria l.) on serum glycemic status, apolipoprotein (apo) b, apoa-i and total antioxidant capacity (tac) in type 2 diabetic patients. this double blind randomized controlled clinical trial was conducted on 41 type 2 diabetic volunteers randomly assign...

a major function of the enterocytes is absorption, processing, and export of dietary lipids into the lymphatic system. pluronic l-81 is a non-ionic hydrophobic surfactant, which specifically inhibits lipid absorption in the intestine when administered in vivo. this compound is therefore an attractive probe to perturb and investigate the molecular and intracellular events in chylomicron assembly...

b a ckground:  to compare the oxidative stress (os) factors in obese and non- obese subjects with type 2 diabetes (t2d) and to evaluate the interaction between the apolipoprotein a-ii (apo a-ii) - 265t > c polymorphism and body mass index (bmi) on os factors. m ethods : in this comparative cross-sectional study, 21 diabetes centers in tehran, iran were studied. 180 patients with t2d were divide...

A turbidimetric method is described for the determination of apolipoproteins A-I, A-II and B on microtitre plates. Regression analysis of the resulting values showed a good correlation to apolipoprotein values determined turbidimetrically on Cobas Bio (apolipoprotein A-I, A-II), and those determined by means of radial immuno diffusion (RID) (apolipoprotein A-I: r = 0.93, y = 1.02 x - 5.0, n = 6...