coincidence of autoimmune diseases such as immune thrombocytopenic purpura (itp) with  immunodeficiencies has  been  reported  previously in  patients  who  suffered  from primary antibody deficiency (pad). but there is no original study on immunological profiles of itp patients to find out their probable immune deficiency. in this case-control study, itp patients’ humoral immunity was investig...

background: the use of organophosphates (ops) in developing countries is rising in large quantities and non-secure methods. this problem not only causes acute poisoning but also may lead to chronic diseases such as polyneuropathy. in iran, 60% of pesticides are organophosphate compounds that may lead to delayed polyneuropathy. objectives: the purpose of the current study was to evaluate delayed...

purpose: to evaluate the prevalence and risk factors of dry eye in the patients referred to an eye clinic in birjand, iran. methods: this cross sectional descriptive-analytical study consisted of 600 patients who were referred to the eye clinic of birjand, iran between september 2010 and september 2011. they were given a simple questionnaire about the risk factors of dry eye including the demog...

purpose: to report a case of isolated corneal squamous cell intraepithelial neoplasia in a patient with unilateral dry eye symptoms. case report: a 48 year old man presented with history of thermal corneal injury in his left eye two years ago, with decreased visual acuity and dry eye symptoms a short time thereafter. he was treated for dry eye with no improvement in symptoms. upon presentation,...

how to cite this article: alavi s. paraneoplastic neurologic syndromes in children: a review article. iran j child neurol. 2013 summer; 7(3): 6- 14. objective paraneoplastic neurological syndromes (pns) were initially defined as neurological syndromes with unknown etiology that often associate with cancer. this broad definition may lead to misconception that any neurological syndrome, which coi...

background: endometrial integrin expression changes might be a reason for implantation failure in polycystic ovarian syndromes (pcos). objective: assessment of integrin genes and proteins expression upon endometrium in the pcos experimental mouse model was the main goal of this study. materials and methods: 30 nmri female mice were equally divided into control, experimental (pcos; received estr...

central giant cell granuloma is a benign, aggressive neoplasm composed of multinucleated giant cells that almost exclusively occurs in the jaws though extra-gnathic incidence is rare.multifocal cgcgs of the jaws are very rare and suggestive of systemic diseases such as hyperparathyroidism,an inherited syndrome such as noonan-like multiple giant cell lesion syndrome or other disorders.very few c...

congenital myasthenic syndromes (cms) are a group of diseases caused by genetic defects affecting neuromuscular transmission and are heterogeneous in inheritance and pathophysiology. these are classified as: 1. presynaptic defects: including choline acetyl transferase deficiency, paucity of synaptic vesicles, lambert-eaton like cms 2. synaptic defect: endplate ach esterase deficiency 3. postsyn...

headache is one of the most common reason that children are referred to the pediatric neurology services. it is said that ten percent of children aged 5 to 15 years have migraine. subsequently, it is essential for clinician to have a through, comprehensive and systematic approach to the evaluation and management of the child or adolescent who complain of headache. this writing aims to explore t...