The catalytic decarboxylation of aromatic carboxylic acids provides an alternative route to generate aryl metal species in situ without using organometallic compounds. Herein, a cationic iridium-catalyzed through CO2 extrusion is described. substrate scope broad, and the reaction proceeds even presence various functional groups. Additionally, potential utility was demonstrated decarboxylative h...

Experiments on hydrothermal degradation of Pyrococcus abyssi biomass were conducted at elevated pressure (40 MPa) over a 200-450 °C temperature range in sapphire reaction cells. Few organic compounds could be detected in the 200 °C experiment. This lack was attributed to an incomplete degradation of P. abyssi cells. On the contrary, a wide range of soluble organic molecules were generated at te...

Carboxylic acids are employed as the vital starting materials in organic synthesis. Various aromatic and aliphatic carboxylic participate electrochemical decarboxylative transformations which CO2 gets liberated generate active carbocation species that reacted with various nucleophiles to produce C−C, C−N, C−O, C−S, C−halogen bonds. L. Tian, Y. Wang et al. discuss recent developments decarboxyla...

In a study of 101 crystal structures of carboxylic acids we have observed a clear trend in the difference between the formally single and formally double C-O bond distances, as observed by X-ray diffraction, with a clear-cut distinction between aromatic acids, where the two distances are similar, and non-aromatic acids, where the two distances distinctly differ by 0.06-0.12 A. A tentative energ...

Transformation of aromatic thioesters into arylboronic esters was achieved efficiently using a rhodium catalyst. The broad functional-group tolerance and mild conditions of the method have allowed for the two-step decarboxylative borylation of a wide range of aromatic carboxylic acids, including commercially available drugs.

Abstract Aromatic carboxylic acids are prone to decarboxylate in high-temperature water (HTW). While the decarboxylation kinetics of several aromatic have been explored, studies on their compatibility with organic syntheses HTW scarce. Herein, we report hydrothermal synthesis (HTS) 2,3-diarylquinoxaline from 1,2-diarylketones and 3,4-diaminobenzoic acid. A detailed study reaction parameters was...

This work demonstrates an alternative method to prepare allylated arenes and aryl-substituted allylic esters via catalytic decarboxylative C-C bond formation using aromatic carboxylic acids and allylic halides and esters.

Depending on the N-heterocyclic carbene catalyst utilized, α-unbranched aldehydes selectively provided amides, esters, or carboxylic acids through oxidation by NCS. The α-unbranched aldehyde underwent these reactions chemoselectively in the presence of an aromatic or α-branched aldehyde.

2-Aminobenzothiazole-6-carboxylic acid (1), on condensation with chloroacetyl chloride yielded 2-(2-chloroacetylamino)benzothiazole-6-carboxylic acid (2), which on amination with hydrazine hydrate yielded in turn 2-(2-hydrazinoacetylamino)benzo-thiazole-6-carboxylic acid (3). Compound 3, on condensation with various aromatic aldehydes afforded a series of 2-{2-[N'-(arylidene)hydrazino]acetylami...