OBJECTIVES Post-transplantation hypertension is prevalent and is associated with increased cardiovascular morbidity and subsequent graft dysfunction. The present study aimed to identify the factors associated with arterial stiffness as measured by the ambulatory arterial stiffness index. METHODS The current study used a prospective, observational, analytical design to evaluate a group of adul...

Central arterial stiffness is associated with incident hypertension and negative cardiovascular outcomes. Obese individuals have higher central blood pressure (BP) and central arterial stiffness than their normal-weight counterparts, but it is unclear whether obesity also affects hemodynamics and central arterial stiffness after maximal exercise. We evaluated central hemodynamics and arterial s...

Arterial stiffness is known as an important surrogate marker of vascular damage and a strong predictor of cardiovascular disease (CVD). Age-related degenerative changes in the intima of large elastic arteries contribute to the loss of arterial elastin and to increased arterial stiffness. Although arterial stiffness is strongly associated with ageing and is clinically shown mostly in older indiv...

The authors evaluated the effects of acute arm-cycling exercise on arterial stiffness of the brachial artery (BA: working limb) and posterior tibial artery (PTA: nonworking limb) in healthy older participants. Eleven participants were tested to evaluate BA and PTA stiffness. Blood pressure (BP), heart rate (HR), and arterial stiffness indices of the BA and PTA measured by Doppler ultrasound wer...

This short review describes the effects of drugs and nonpharmacologic treatments on large artery stiffness in clinical trials. Arterial stiffness is generally accepted as a predictive factor for cardiovascular morbidity and mortality. The drug-induced reduction in arterial stiffness may parallel the reduction in cardiovascular work. This review summarizes the discussion of a task force that wor...

Increased arterial stiffness is an independent predictor of cardiovascular disease independent from blood pressure. Recent studies have shed new light on the importance of inflammation on the pathogenesis of arterial stiffness. Arterial stiffness is associated with the increased activity of angiotensin II, which results in increased NADPH oxidase activity, reduced NO bioavailability and increas...

Increased central arterial stiffness, involving accelerated vascular ageing of the aorta, is a powerful and independent risk factor for early mortality and provides prognostic information above and beyond traditional risk factors for cardiovascular disease (CVD). Central arterial stiffness is an important determinant of pulse pressure; therefore, any pathological increase may result in left ven...

Arterial stiffness plays a key role in the pathophysiology of the cardiovascular system. Some indices of arterial stiffness (pulse wave velocity, augmentation index, characteristics of central blood pressure waveform) may be presently calculated and evaluated in the clinical setting. Age and blood pressure are the two major clinical determinants of increased arterial stiffness, while molecular ...

BACKGROUND Arterial stiffness is a risk factor for stroke and myocardial infarction. We investigated whether carotid arterial stiffness is related to other localizations of manifest arterial disease. METHODS Carotid artery stiffness was measured by ultrasonography as the change in diameter in systole relative to the diastolic diameter in patients enrolled in the Second Manifestations of Arter...

Acampa et al. investigated arterial stiffness in patients with deep intracerebral hemorrhage (ICH) in comparison with that in patients with lobar ICH. The arterial stiffness index was significantly higher in the patients with deep ICH than in the patients with lobar ICH. This is a well-written study. However, we want to mention the associated drugs used by patients that can affect arterial stif...