INTRODUCTION Pseudo-Foster Kennedy syndrome is a triad consisting of ipsilateral optic atrophy, contralateral optic disc edema, and ipsilateral anosmia in the absence of an intracranial mass. Vitamin B12 plays an important role in DNA synthesis, and its deficiency causes peripheral neuropathy, myeloneuropathy, and, very rarely, optic neuropathy. CASE PRESENTATION In this study, we describe a ...

BACKGROUND Protein Z is a glycoprotein that acts as a co-factor for the inhibition of activated coagulation factor X. Protein Z circulating in abnormal levels has been associated with increased risk for acute ischemic events. Non-arteritic Anterior Ischemic Optic Neuropathy (N-AION) is caused by acute ischemic infarction of the optic nerve head, supplied by the posterior ciliary arteries. OBJ...

In this review, we comprehensively describe ophthalmic diseases with mitochondrial DNA mutation such as Leber's hereditary optic neuropathy (LHON), progressive external ophthalmoplegia (PEO) and Kearns-Sayre Syndrome (KSS). Ocular involvement is a prominent clinical feature of various mitochondrial diseases as well. The known mitochondrial disorders such as Mitochondrial encephalomyopathy, lact...

Anterior ischemic optic neuropathy is an acute ischemic disease of vascular origin whose treatment demands urgent application of an appropriate therapy. The research included 56 patients with an acute form of anterior ischemic optic neuropathy with 50 of them classified as idiopathic types while 6 had the arteritic form of the disease. In this paper, we analyze the therapeutic significance and ...

Purpose: ‘This study describes hemodynamic characteristics of the retrobulbar circulation in ten eyes with acute anterior ischemic optic neuropathy (AION), in order to better understand Ihe natural history of this disease. Methods: Color Doppler imaging was used to measure the peak systolic blood flow velocities and vascular resistance (resistive index) within the central retinal, ophtalmic, an...

Recent advances in understanding the effects of hyperbaric oxygen (HBO) on retinal anoxia gave rise to new interest in the possibility of using it as therapeutic treatment for ischemic conditions of the retina and optic nerve. Two patients with non-arteritic anterior ischemic optic neuropathy due to a high-grade ophthalmic artery stenosis were treated with HBO at 2 atm abs in an effort to incre...

Purpose: ‘This study describes hemodynamic characteristics of the retrobulbar circulation in ten eyes with acute anterior ischemic optic neuropathy (AION), in order to better understand Ihe natural history of this disease. Methods: Color Doppler imaging was used to measure the peak systolic blood flow velocities and vascular resistance (resistive index) within the central retinal, ophtalmic, an...