Geoduck clams (Panopea generosa) are an increasingly important fishery and aquaculture product along the eastern Pacific coast from Baja California, Mexico, to Alaska. These long-lived clams are highly fecund, although sustainable hatchery production of genetically diverse larvae is hindered by the lack of sexual dimorphism, resulting in asynchronous spawning of broodstock, unequal sex ratios, ...

In this paper a new wavelet shrinkage technique is proposed and investigated. When data consist of a multiplicity of related noisy signals, we propose a wavelet-based shrinkage estimation procedure to summarize all data components into a single regularized and representative signal (\base-line"). This fusion of information from di erent runs is done via Stein-type shrinkage rule resulting from ...

OBJECTIVE Several studies have shown that knee OA is associated with obesity, physical stress at work, traumatic knee injuries, heredity and female gender. However, the body of such evidence comes from cross-sectional or case-control studies, and from only a few follow-up studies, mostly of short duration. Based on the nationwide Mini-Finland Health Survey, we analysed the potential risk factor...

The Ediacara biota include macroscopic, morphologically complex soft-bodied organisms that appear globally in the late Ediacaran Period (575-542 Ma). The physiology, feeding strategies, and functional morphology of the modular Ediacara organisms (rangeomorphs and erniettomorphs) remain debated but are critical for understanding their ecology and phylogeny. Their modular construction triggered n...

Dynamic contrast-enhanced MRI has been proven to be a valuable technique in cancer imaging. The poorly formed and leaky vessels formed during angiogenesis to supply tumors facilitate an increased uptake of intravenously administered contrast agents in comparison to normal vasculature. The use of mathematical modeling techniques on the change in tumor signal intensity as a function of time provi...

Man is, irl many ways, very unsuitable as an object for the study of genetics. Families are too small for dependable determination of ratios, desired test matings cannot be made, and study of more than a very few generations for 'my particular purpose is not often possible, The social implications of human genetics are so great, however, that the subject must be investigated; and there are some...

Anthropogenic noise impacts behaviour and physiology in many species, but responses could change with repeat exposures. As repeat exposures can vary in regularity, identifying regimes with less impact is important for regulation. We use a 16-day split-brood experiment to compare effects of regular and random acoustic noise (playbacks of recordings of ships), relative to ambient-noise controls, ...

The extensive similarities between the genomes of human and model organisms are the foundation of much of modern biology, with model organism experimentation permitting valuable insights into biological function and the aetiology of human disease. In contrast, differences among genomes have received less attention. Yet these can be expected to govern the physiological and morphological distinct...

The increased sensitivity of immunofixation electrophoresis (IFE) over prior electrophoretic methods has led to renewed interest in the study of free light chains. Here, we discuss problems associated with the identification of monoclonal free light chains (Bence Jones proteins) in urine. Besides reviewing the nature of the sample specimens and the assays themselves, we discuss the physiology, ...