We tested a mixture of Tridax procumbens, known for its direct action against Leishmania mexicana, and Allium sativum, known for its immunomodulatory effect, as an alternative to treat cutaneous leishmaniasis. Acute oral toxicity was tested with the Up-and-Down Procedure (UDP) using a group of healthy mice administered with either T. procumbens or A. sativum extracts and compared with a control...

Previous phytochemical analysis of methanolic extract of C. procumbens L. has indicated the presence of steroid, flavonoid and terpenoid types of compounds. Since these compounds are of pharmacological interest, coupled with the use of this plant in traditional medicine, prompted us to check C. procumbens L for possible antioxidant activity by DPPH, total antioxidant, total phenolic and reducin...

Calotropis gigantea Linn and Tridax procumbens Linn, are well documented medicinal plants distributed in Asia and Africa and are useful for many ailments. The anti-inflammatory activity of low dose of the aqueous extract of T. procumbens and ethanolic extract of C.gigantea were assessed on carrageenan induced paw edema and compared with standard drug Ibuprofen. The oral administration of 400mg/...

ETHNOPHARMACOLOGICAL RELEVANCE Gynura procumbens is commonly used as a traditional medicinal plant in Malaysia for treatment of many diseases. To investigate the chemopreventive properties of Gynura procumbens on azoxymethane (AOM)-induced aberrant crypt foci (ACF) in rats. METHODS Five groups of adult male rats were used in this experiment. Normal/control group; the rats were injected subcut...

Kidney stones are from dietary minerals in the urine and there is no suitable drug to use in clinical therapy. Traditionally it is known that Tridax procumbens leaf juice possess antilithiatic property. Calcium oxalate (CaOx) crystal nucleation was significantly inhibited by the presence of Tridax procumbens extract, when compared to control. The effect of leaf extract on crystal growth assay p...

Essential oil from Gaultheria procumbens is mainly composed of methylsalicylate (MeSA) (>96%), a compound which can be metabolized in plant tissues to salicylic acid, a phytohormone inducing plant immunity against microbial pathogens. The potential use of G. procumbens essential oil as a biocontrol agent was evaluated on the model plant Arabidopsis thaliana. Expression of a selection of defense...

Harpagophytum procumbens, also known as Devil's Claw, has historically been used to treat a wide range of conditions, including pain and arthritis. The study was designed to investigate whether H. procumbens extracts exhibit analgesic effects in plantar incision and spared nerve injury (SNI) rats. The whole procedure was performed on male SD rats. To evaluate pain-related behavior, we performed...

The genus Harpagophytum has two species: H. procumbens which is an important medicinal plant in southern Africa, and H. zeyheri. Genetic diversity in 96 samples, obtained by germinating seeds collected from Botswana, was assessed using six inter-simple sequence repeat (ISSR) and 10 random amplified polymorphic DNA (RAPD) primers. These DNA markers yielded a total of 138 polymorphic bands. Polym...

BACKGROUND Diabetes is a metabolic disorder affecting carbohydrate, fat and protein metabolism. Tridax procumbens Linn. (Family-Asteraceae; common name-Dhaman grass) is common herb found in India. Traditionally, the tribal inhabitants of Udaipur district in Rajasthan (India) uses the leaf powder (along with other herb) orally to treat diabetes. There is a need to evaluate extracts of this plant...

BACKGROUND The Acanthaceae family is an important source of therapeutic drugs and ethno medicines. There are many famous medicinal plants from this family, such as Andrographis paniculata, Baphicacanthus cusia, and Dicliptera chinensis. Justicia procumbens (J. procumbens) is widely distributed in tropical and sub-tropical of the world. It has long been used in traditional Chinese medicine for c...