BACKGROUND AND PURPOSE Until now, most studies of brain injury related to term neonatal encephalopathy have focused on the cerebrum and ignored the cerebellum. We sought to evaluate whether cerebellar injury occurs in term asphyxiated neonates. MATERIALS AND METHODS Asphyxiated neonates treated with hypothermia were enrolled prospectively. Severity of brain injury in the cerebrum was scored o...

BACKGROUND Intraventricular hemorrhage (IVH) is uncommon in term newborns. Asphyxia and hypothermia have been mentioned separately as possible risk factors of IVH, since they might cause fluctuations of cerebral blood flow. The aim of this study was to assess the incidence, the timing, and the risk factors of intraventricular hemorrhage (IVH) in term asphyxiated newborns treated with hypothermi...

Perinatal asphyxia is a cause of significant morbidity among full term infants, but breathing abnormalities after an asphyxic insult have not been studied. This report details breathing patterns of 16 full term asphyxiated infants, during the first week of life who were studied by transthoracic impedance pneumocardiograms. Pneumocardiograms were abnormal in 69% of infants in the asphyxiated gro...

OBJECTIVE: To verify the effect of perinatal asphyxia on thyroid hormone levels in term newborn infants. METHODS: We carried out a case-control study with 17 term and asphyxiated (A) and 17 term and control (N) newborn infants at the Hospital de Clínicas de Porto Alegre. Patients were paired according to color of skin, sex, type of delivery, gestational age, and weight at birth. We collected um...

Diving mammals share with fetal and newborn animals a high resistance to asphyxia when compared, respectively, with terrestrial and adult animals. Adaptations for conservation or sparing of oxygen and for adjustment to the effects of accumulated metabolic products, such as carbon dioxide and hydrogen ions, have been discovered in both diving marine mammals and asphyxiated terrestrial species. T...

Neonatal asphyxia can cause irreversible injury of multiple organs resulting in hypoxic-ischemic encephalopathy and necrotizing enterocolitis (NEC). This injury is dependent on time, severity, and gestational age, once the preterm babies need ventilator support. Our aim was to assess the different brain and intestinal effects of ischemia and reperfusion in neonate rats after birth anoxia and me...

OBJECTIVE Hypoxic ischemic encephalopathy (HIE) is a major cause of permanent neurological disabilities. Perinatal asphyxia may induce neonatal mortality after birth or neurological impairment among survivors. There are no reliable methods for identifying infants at risk for this disorder. METHODS We measured the ratio of lactate/creatinine (L/C) in urine by proton nuclear magnetic resonance ...

OBJECTIVE To determine the proportion of children aged <2 years who have been asphyxiated presenting with epistaxis in the absence of trauma or medical explanation and to identify the characteristics of the clinical presentation indicative of asphyxiation. STUDY DESIGN An all-language systematic review was conducted by searching 10 databases from 1900 to 2015 and gray literature to identify h...

Acute kidney injury (AKI) is a recognized complication of birth asphyxia. Early recognition of AKI is important in asphyxiated neonates as it helps in early intervention and appropriate management. The aim of this study was to determine the pattern of AKI in asphyxiated neonates and its relation to the grade of Hypoxic Ischemic Encephalopathy (HIE). This was a prospective hospital based study, ...