BACKGROUND There is growing evidence that damage to spermatozoa by reactive oxygen species (ROS) play a key role in male infertility. The aim of the present study was to assess seminal plasma levels of total antioxidant capacity (TAC), free 8-Isoprostane and activities of catalase and superoxide dismutase (SOD) in men with asthenozoospermia, asthenoteratozoospermia and oligoasthenoteratozoosper...

Background Estrogens biosynthesis in ejaculated spermatozoa is an autonomous process that may influence sperm functions. The purpose of this study was to evaluate the relationship between the expression of aromatase, sperm quality and seminal neutral α–glucosidase marker in semen of Tunisian infertile men. MaterialsAndMethods Fifty seven men were investigated: they were composed of two groups: ...

background: use of cellular phones emitting radiofrequency electromagnetic field (rf-emf) has been increased exponentially and become a part of everyday life. this study aimed to investigate the effects of in vitro rf-emf exposure emitted from cellular phones on sperm motility index, sperm dna fragmentation and seminal clusterin (clu) gene expression. materials and methods: in this prospective ...

Abstract Study question Is there any novel variant in CFAP69 gene related to multiple morphological abnormalities of sperm flagella (MMAF) humans? Summary answer We identified a loss-of-function Chinese man with MMAF and intracytoplasmic injection (ICSI) is favorable for the affected couple. What known already specific type asthenoteratozoospermia characterized by immotile malformed spermatozoa...

Abstract Study question Can novel mutations of DRC1 gene affect the sperm morphology in humans and how about outcomes assisted reproductive therapy affected patients? Summary answer An infertile man with multiple morphological abnormalities flagella caused by biallelic has good fertility after intracytoplasmic injection. What is known already The nexin-dynein regulatory complex (N-DRC) function...

background: there is growing evidence that damage to spermatozoa by reactive oxygen species (ros) play a key role in male infertility. objective: the aim of the present study was to assess the antioxidant status of seminal plasma by measuring total antioxidant capacity (tac) and activities of catalase and superoxide dismutase (sod) in men with asthenozoospermia, asthenoteratozoospermia and olig...

Chronic alcohol consumption and cigarette smoking adversely affect male reproductive health. This work highlights the influence of both on the sperm quality of infertile male partners. This prospective study was conducted on semen samples of alcoholics(Group1), smokers-(Group2), habit of both-(Group-3), controls-(Group4). Samples were analysed following WHO guidelines including the percentage o...