The skin is one of the target organs that are most often involved in food hypersensitivity reactions. Clinical manifestations of food hypersensitivity in the skin range from symptoms of atopic dermatitis, urticaria, angioedema to dermatitis herpetiformis, and a masquerader of food allergy, the Frey’s syndrome. All present with typical skin manifestations of their foodallergic reactions. Three c...

A fundamental result in the evolutionary-game paradigm of cyclic competition in spatially extended ecological systems, as represented by the classic Reichenbach-Mobilia-Frey (RMF) model, is that high mobility tends to hamper or even exclude species coexistence. This result was obtained under the hypothesis that individuals move randomly without taking into account the suitability of their local...

This case report documents the case of a 41-year-old Caucasian woman who developed a Frey's syndrome after elective thyroidectomy. This patient developed a sudden redness on one side of the face in the recovery room after a total thyroidectomy under general anaesthesia. All other vital signs of the patient remained normal. There were no signs of infection. After a few hours the symptoms disappe...

BACKGROUND After parotid surgery, traumatized auriculotemporal, postganglionic, parasympathetic nerve fibers reinnervate the sweat glands and subcutaneous vessels resulting in gustatory sweating and facial flushing. Because Frey’s syndrome (FS) does not spontaneously resolve, multiple prevention and treatment strategies have been proposed. The literature supports evidencebased best practices fo...

Hyperhidrosis or gustatory sweating in the region of the parotid gland was first mentioned by Kastremsky in 1740, Duphenix in 1757 and then by Baillarger in 1853. It was, however, the Polish neurologist Lucja Frey who described this condition as a new syndrome in 1923 [1,2]. Frey syndrome (FS) is characterized by localized cervicofacial hyperhidrosis and erythema during mastication in the area ...

BACKGROUND The auriculotemporal nerve has been identified as one of the peripheral trigger sites for migraine headaches. However, its distal course is poorly mapped following emergence from the parotid gland. In addition, a reliable anatomical landmark for locating the potential compression points along the course of the nerve during surgery has not been sufficiently described. METHODS Twenty...

The auriculotemporal nerve is a sensory branch extending from the posterior section of the mandibular nerve trunk. Its nerve roots form a short trunk, which gives off a number of branches, innervating: the temporomandibular joint, the temporal region, structures of the external ear: auricle, and external acoustic meatus, and the parotid gland. It also conducts excretory fibres to the buccal...

Abstract A 3-year-old girl presented with an 18-month history of left-sided facial erythema involving her left cheek. This occurred within seconds to minutes after eating food and lasted between 5 20 min before complete spontaneous resolution without any associated symptoms. The flushing was not confined a particular type. She born at 37 weeks via forceps-assisted delivery, which had resulted i...

BACKGROUND Clinical experience with surgical decompression of specific peripheral nerves in the head and neck for the relief of migraine headache symptoms has proven to be effective in most patients. Some patients, however, continue to have residual symptoms after these procedures. In an effort to better understand potential etiologies for failure of treatment, an investigation was performed to...