This review discusses the accumulated evidence that pro-opiomelanocortin (POMC) gene products as well other pituitary neuropeptides derived from related genes (Proenkephalin, PENK; Prodynorphin, PDYN, and Pronociceptin, PNOC) can exert direct effects on B lymphocytes to modulate their functions. We also available data receptor systems might be involved in transmission of such hormonal signals c...
