OBJECTIVE To investigate the role of HLA-B and HLA-DR genes as contributors to genetic susceptibility and clinical expression of the spondyloarthropathies (SpA) in the Mexican population. METHODS The study included 172 patients with SpA (undifferentiated SpA 83, ankylosing spondylitis (AS) 64, and reactive arthritis 25) and 99 healthy controls. The HLA-B and HLA-DR alleles were detected by th...

Previous sea level rise (SLR) assessments have excluded the potential for dynamic ice loss over much of Greenland and Antarctica, and recently proposed "upper bounds" on Antarctica's 21st-century SLR contribution are derived principally from regions where present-day mass loss is concentrated (basin 15, or B15, drained largely by Pine Island, Thwaites, and Smith glaciers). Here, we present a pr...

Many neurons that contain a classical neurotransmitter also contain modulatory peptides, but it has been difficult to establish unequivocally that these peptides are functional cotransmitters. Here, we provide evidence for functional cotransmission in a neuromuscular system of Aplysia. Using immunocytochemical techniques, we localize members of two peptide families, the small cardioactive pepti...

Bl Introduction Bl Acknowledgments B3 Description and interpretation of individual quartzite occurrences B3 Hamilton Mounds B3 Necedah area B6 Baraboo area B6 Waterloo area BIO Vesper quarry Bll Veedum area Bll Conglomerate at Hamann Creek B12 Rib Mountain B12 Quartzite at McCaslin and Thunder Mountains B12 Barron Quartzite and quartzite at Flambeau Ridge B14 Summary of interpretations B15 Age ...

D. J. SMITH†, E. A. GAFFNEY, J. R. BLAKE AND J. C. KIRKMAN-BROWN School of Mathematics and Reproductive Biology and Genetics, College of Medicine, Dentistry and Health Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK Centre for Human Reproductive Science, Birmingham Women’s NHS Foundation Trust, Metchley Park Road, Edgbaston, Birmingham B15 2TG, UK Centre for Mathematical B...

Edwin A. Yates, Martin O. Jones, Caroline E. Clarke, Andrew K. Powell, Simon R. Johnson, Adrian Porch, Peter P. Edwards and Jeremy E. Turnbull School of Biosciences, University of Birmingham, Birmingham, UK B15 2TT School of Chemical Science and the School of Metallurgy and Materials, University of Birmingham, Birmingham, UK B15 2TT Electronics Division, School of Engineering, Queen’s Building,...

Compared with the MHC of typical mammals, the chicken MHC is smaller and simpler, with only two class I genes found in the B12 haplotype. We make five points to show that there is a single-dominantly expressed class I molecule that can have a strong effect on MHC function. First, we find only one cDNA for two MHC haplotypes (B14 and B15) and cDNAs corresponding to two genes for the other six (B...

In this study, The model Mazda WL diesel engine,4-cylinder, 4 straight-line cylinder with biodiesel blends ratio of 0%, 15%, 20%, 25%, 30% derived from rubber seed oil and DO has been simulated on ANSYS FLUENT software to analyze fuel consumption characteristics. Experimental engine using (DO) (B15, B20, B25, B30) for a installed 2500 Ford Ranger cars. simulation results show that the average i...

Unlike chronic myeloid leukemia, patients with acute lymphoblastic leukemia (ALL) with Philadelphia chromosome (Ph+) do not respond well to Imatinib or tyrosine kinase inhibitors (TKI). In addition, TKI might induce resistant mutations in kinase domain (KD) of ABL in patients with relapsed diseases. Of the histone deacetylase (HDAC) inhibitors, suberoylanilide hydroxamic acid (SAHA) has shown t...