An 81-year-old woman presented with a one-week history of pyrexia (38.6°C), headache, acalculia, and hemianopia. Laboratory examinations revealed an elevated leukocyte count (10,000/mm), neutrophil count (8,200/mm), and erythrocyte sedimentation rate (43 mm/h). CSF study revealed pleocytosis (33/mm) and an elevated protein level (402 mg/dL). MRI showed leptomeningeal gadolinium enhancement (arr...

Two hundred and eighty nine unrelated Marathas residing in Mumbai, Maharastra, (Western India) were studied for HLA A, B, C and DR locus antigen profiles. The HLA antigen maximum likelihood gene frequencies of HLA A1, A2, A9 (24), A11, A19 (33), B5, B7, B35, B40 (61), Cw3, Cw6, DR2, DR5, DR7, DQ1 and DQ2 were increased while that of HLA A3, A10 (26), A36, B8, B13, B16 (38), B18, B21, B22 (55), ...

Tonic stimuli can elicit rhythmic responses. The neural circuit underlying Aplysia californica consummatory feeding was used to examine how a maintained stimulus elicits repetitive, rhythmic movements. The command-like cerebral-buccal interneuron 2 (CBI-2) is excited by tonic food stimuli but initiates rhythmic consummatory responses by exciting only protraction-phase neurons, which then excite...

Background. Although eradicated in Portugal, malaria keeps taking its toll on travelers and migrants from endemic countries. Disease notification is mandatory but is compromised by underreporting. Methods. A retrospective study on malaria hospitalizations for 10 consecutive years (2000-2009) was conducted. Data on hospitalizations and notifications were obtained from Central Administration of H...

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OBJECTIVE To evaluate the possible relationship between HLA alleles and bony ankylosis of the spine (bamboo spine) in Taiwanese patients with ankylosing spondylitis (AS). METHODS A small cohort of HLA-B27 positive AS patients was conducted to analyze the effects of alleles {and haplotypes} on the development of bamboo spine. DNA typing of HLA class I and class II genes were performed by SSP m...

The Zika virus disease is an Aedes mosquito-borne disease caused by the ZIKA virus. The unavailability of vaccines or proper chemotherapeutic treatment emphasizes the need for the development of preventive and therapeutic vaccines. T cell specific epitopes have been used as vaccine candidates to generate desired immune responses against a variety of viral pathogens. Herein, the immune-informati...

Background—DiVuse panbronchiolitis (DPB), characterised by progressive sinobronchial sepsis, is well characterised in Japanese subjects but not in other ethnic groups. The experience with DPB in seven Chinese patients is described and the clinical profiles compared with those of Japanese subjects. Methods—Seven Chinese patients (three women; mean (SD) age 48(18.6) years, all never smokers) who ...

This paper proposes a theory of why the state enacted social policy that regulated the length of the working day in 19th century industrial England. This paper will argue that, far from being capable of self-regulation, the capitalist labor market during Britain’s industrial revolution is best conceptualized as consisting of two major social coordination problems resulting from conflicting inte...