Immune system plays an important role in pathogenesis of diabetes (DM). Besides hypoglycaemics, rasayanas are indicated in the management of DM. In several studies the immunomodulatroy potentials of rasayanas have been proved. A clinical trial of three rasayana drugs, Asparagus recemosus (AR). Bacopa monnieri (BM) and Centella asiatica (CA) was carried out in diabetics. In this study, diabetics...

ETHNOPHARMACOLOGICAL RELEVANCE Bacopa monnieri has a long history in Ayurvedic medicine for neurological and behavioral defects. To assess its efficacy in improving cognitive function. MATERIALS AND METHODS MEDLINE, EMBASE, CINAHL, AMED, Cochrane Central of clinical trial, WHO registry, Thai Medical Index, Index Medicus Siriraj library and www.clinicaltrial.gov were searched from the inceptio...

Methylmercury (MeHg) is a highly toxic environmental pollutant that causes severe neurological disorders. Considering the neuroprotective property of Bacopa monniera, this study was aimed to evaluate protective effect of Bacopa monniera extract (BME) against MeHg induced mitochondrial dysfunction. Rats were exposed to MeHg by gavage (5mg/kg, b.w) and BME was administered (40 mg/kg, orally) 1 ho...

s Presented 1. Amee Krishnakumar, Pretty Mary Abraham and C. S. Paulose. Enhanced 5-HT2C receptor gene expression in the cerebral cortex of pilocarpine inducedepileptic rats: Neuroprotective role of Bacopa monnieri. InternationalSymposium on Regenerative Neuroscience and Annual Meeting of Societyfor Neurochemistry (India) concurrently held at National Institute of MentalHeal...

A hydroethanolic extract (HE-ext) of Bacopa monnieri (BM) was studied for antinociceptive effect in the animal models of acetic-acid-induced writhing test and antilocomotive effect in mice. Standard centrally-acting analgesic, morphine (MP), and peripherally-acting one, diclofenac (Diclo), were also tested along with the extract for comparison. The extract exhibited significant antinociceptiv...

OBJECTIVE Bacopa monniera (BM), a traditional Ayurvedic medicine has been used in treatment for a number of disorders, particularly those involving anxiety, intellect and poor memory. The current study examined the effects of standardized extract of Bacopa monniera on the dendritic morphology in adult rats of hippocampal CA3 neurons, one of the regions concerned with learning and memory. MATE...

Bacopa Monnieri (L) penn. Belongs to the family scrophulariaceae is commonly used in Ayurvedic system of medicine to treat various disease. The present stud examines the anti-tumous effect of ethanolic extract of whole plant bacopa monnieri (L) (EEMB) by in vitro short term chemosensitivity and in vivo tumous model test systems. EEBM dose dependently inhibited the proliferation of transformed c...

a hydroethanolic extract (he-ext) of bacopa monnieri (bm) was studied for antinociceptive effect in the animal models of acetic-acid-induced writhing test and antilocomotive effect in mice. standard centrally-acting analgesic, morphine (mp), and peripherally-acting one, diclofenac (diclo), were also tested along with the extract for comparison. the extract exhibited significant antinociceptive ...

Dementias and other severe cognitive dysfunction states pose a daunting challenge to existing medical management strategies. An integrative, early intervention approach seems warranted. Whereas, allopathic treatment options are highly limited, nutritional and botanical therapies are available which have proven degrees of efficacy and generally favorable benefit-to-risk profiles. This review cov...