PURPOSE To report a case of endophthalmitis following 25-gauge transconjunctival sutureless vitrectomy. DESIGN Observational case report. METHODS An 87-year-old male who underwent sutureless 25-gauge vitrectomy developed unilateral endophthalmitis. Vitreous culture revealed Staphylococcus coagulase-negative bacteria. He was subsequently treated with intravitreal antibiotics and oral prednis...

PURPOSE Infectious endophthalmitis is characterized by neutrophil migration into the eye. The purpose of this study was to determine whether systemic neutrophil depletion mitigates the ocular influx of neutrophils during the early phases of experimental endophthalmitis. METHODS Endophthalmitis was induced in rats by intravitreal injection of Staphylococcus aureus. Animals received a single sy...

BACKGROUND We report a case of bacterial endophthalmitis caused by an intraocular cilium in a patient without any history of trauma or ocular surgery. FINDINGS A 32-year-old Caucasian male showed symptoms of orbital myositis and scleritis, with no intraocular inflammation in the right eye. The patient had been treated with infliximab for Crohn's disease. Three weeks after initiation of oral p...

Endophthalmitis is an infection of the posterior segment of the eye that frequently results in loss of vision. This devastating result occurs despite prompt and often aggressive therapeutic and surgical intervention. Over the past decade, research has centered on determining the bacterial and host factors involved in this potentially blinding disease. The initial focus on the bacterial factors ...

The incidence of bacterial endophthalmitis has been 3-6% after cataract extraction in the eye camps of South India from 1961-75. During this time 50 791 cases were operated using systemic and topical chloramphenicol prophylaxis. This study evaluated the prophylactic intracameral injection of 50 microng of gentamicin in eye camp cataract extractions. Only 6 of 1626 patients treated with intracam...

Postoperative endophthalmitis is a rare but potentially devastating complication of intra-ocular surgery. Most cases are caused by bacterial infection. The clinical presentation of endophthalmitis can be classified as acute postoperative endophthalmitis, chronic postoperative endophthalmitis, and bleb-associated endophthalmitis. They each have a different aetiology, treatment, and prognosis. Th...

in order to determine the effects of intraocular 0.05% povidone-iodine preparation in the prevention of bacterial endophthalmitis in a rabbit model, 28 albino rabbits were randomly assigned to 4 equal groups. a concentration of 5x 108 organisms (0.03 ml) in logarithmic growth phase of s. epidermidis, s. aureus, proteus mirabilis and pseudomonas aeruginosa, were injected separately in the anteri...

PURPOSE Postsurgical endophthalmitis is a sight-threatening problem. We introduce a simple approach by using a single application of thermoresponsive controlled-release microspheres, loaded with moxifloxacin, to prevent bacterial endophthalmitis in a rabbit endophthalmitis prevention model. METHODS We separated 24 rabbits into 3 treatment groups in which topical drop treatment was placed onto...

Background: Bacterial endogenous endophthalmitis (BEE) is uncommon and severe. Few patients who have this disease are initially misdiagnosed. Its victims usually have an underlying disease which predisposes them to infection. Blood and vitreous cultures are the most frequently used media of establishing the diagnosis. Staphylococcus aureus, group B streptococci, Streptococcus pneumonia and List...